Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 678-448-7 | CAS number: 3084-53-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 06 August to 10 September 2021
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch No.: 20SP9-4
Appearance: White solid
Purity: 98.6% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): A fresh sample of activated sludge was collected from the aeration tank of Shenyang North Sewage Treatment Plant two days before the test exposure was started.
- Preparation of inoculum for exposure: On the day of sludge collection, coarse particles were removed by filtration through a fine sieve and the sample was settled. After the supernatant was discarded, the sludge was washed twice with mineral medium and the concentrated sludge was suspended in mineral medium.
- Concentration of sludge: The suspended sludge was prepared with mineral medium to yield a concentration of 4.0 g/L as SS. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 62.8 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: 250 mL flask
- Number of culture flasks/concentration: 2 replicates
CONTROL AND BLANK SYSTEM
- Inoculum blank: Test vessels containing only 250 mL inoculated mineral medium were prepared in duplicate and served as inoculum controls identified as IC-1 and IC-2.
- Toxicity control: Toxicity control test vessel contained both test item and reference item. Both, a weighed amount (0.0157 g) of test item and a weighed amount (0.0125 g) of reference item were added into test vessel. The concentration of test item was 62.8 mg/L (equivalent to 86.7 mg/L as ThODNH3) and the concentration of reference substance was 50.0 mg/L (equivalent to 83.5 mg/L as ThOD). The concentration expressed as total ThOD was 170.2 mg/L. One replicate (toxicity control identified as TC) was sufficient. - Reference substance:
- benzoic acid, sodium salt
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 78.1
- Sampling time:
- 28 d
- Details on results:
- The average biodegradation of test item after 6 days and 1 hour was 10.7% (2 replicates), which was the initial time on which 10% biodegradation was exceeded, and when the 10-day window began. The average biodegradation were 74.9% within 10-day window (after 16 days and 2 hours), and 78.1% after 28 days.
- Results with reference substance:
- The biodegradation of the reference substance (Sodium benzoate) was 84.6% after 14 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The percentage biodegradation of Test item within 10-day window exceeded the pass level of 60% ThOD. The test item can be assumed to be readily biodegradable.
- Executive summary:
The ready biodegradability test of Test item was conducted with unacclimatised sewage micro-organisms by measuring oxygen consumption over the 28-day test period, according to OECD Guideline 301F.
Based on the results, the percentage biodegradation of Test item within 10-day window exceeded the pass level of 60% ThOD. The test item can be assumed to be readily biodegradable under the described test conditions.
Reference
Description of key information
The ready biodegradability test of Test item was conducted with unacclimatised sewage micro-organisms by measuring oxygen consumption over the 28-day test period, according to OECD Guideline 301F.
Based on the results, the percentage biodegradation of Test item within 10-day window exceeded the pass level of 60% ThOD. The test item can be assumed to be readily biodegradable under the described test conditions.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.