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EC number: 500-241-6 | CAS number: 69011-36-5 1 - 2.5 moles ethoxylated
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (30d): 0.1 - 1 mg/L QSAR estimation)
Key value for chemical safety assessment
Additional information
The calculated PEC/PNEC ratios for the freshwater and marine compartment were < 1 for all uses. In conclusion, the environmental exposure assessment for the substance indicates no risk for the aquatic compartment (all RCR < 1; please refer to Chapter 9 and 10 of the Chemical Safety Report for detailed information). In accordance to column 2 of Annex IX, section 9.4 of Regulation (EC) No. 1907/2006, no further tests on the effects of the substance to terrestrial organisms are needed and consequently further testing was omitted.
Experimental data on long-term toxicity of Isotridecanol, ethoxylated, < 2.5 EO to fish are not available. The available acute toxicity data on fish, aquatic invertebrates and algae indicate that Daphnia are the most sensitive organisms with an effect concentration EL50 (48h) of 0.544 mg/L (geom. mean measured). For fish a LL50 (96h) > 1.1 mg/L (geom. mean measured) was determined toxic effects were not observed. The ErC50 (72h) determined for algae was 3.4 mg/L (meas. arith. mean). Experimental data on the chronic toxicity are available for aquatic invertebrates and algae. The NOEC (21 d) determined for the reproduction rate of Daphnia magna is 0.218 mg/L (TWA). The ErC10 (72h) for algae is 1.33 mg/L (meas. arith. mean). The chronic effect concentrations for fish, calculated by QSAR, and the available experimental data on D. magna and algae are in the same order of magnitude. The chronic toxicity to fish was estimated by QSAR using a mixtureadditivityapproach. The QSAR model is based on the log Kow as predictor variable. Alcohol ethoxylates are assumedaffect aquatic organismsbynon-polar narcosis and thus the effects are related to the log Kow.The EC10 calculated by QSAR is in the range of 0.1 – 1 mg/L (EC10 (30 d): 0.236 mg/L). A higher sensitivity of fish compared to daphnia or algae is not likely.
Conclusion
The environmental exposure assessment indicates no risk for the
aquatic compartment.
The estimated chronic effect concentration for fish and the
experimentally determined NOEC for aquatic invertebrates are in the same
order of magnitude. Based on the available acute data set, it is not
expected that fish are more sensitive than daphnia.
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