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Diss Factsheets
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EC number: 303-152-9 | CAS number: 94158-79-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- Zahn-Wellens-Test
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 11 February to 11 March 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Conducted to a recognised OECD Guideline and to GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.9 (Biodegradation: Zahn-Wellens Test)
- Qualifier:
- according to guideline
- Guideline:
- other: ISO 9888 (1991)
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Not applicable. - Oxygen conditions:
- anaerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Kläranlagen der Hoechst AG: Werk Hächst und Werk Kelsterbach im Verhältnis 1: 1 gemischt.
- Preparation of inoculum for exposure:
- Pretreatment: Vorbehandlung entsprechend EG Vorschrift (1.6.1.3).
- Concentration of sludge: 9.4 g dry substance/L. Damit lag die Einsatzmenge im Test bei 658 mg/l (Trockensubstanz) und im geforderten Bereich des 2,5- bis 4-fachen des eingesetzten Kohlenstoffgehaltes (berechnet gemäß Stammläsungsanalyse).
- Initial cell/biomass concentration: 70 ml Schlammsuspension mit 100 g NS/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 202.7 mg/L
- Based on:
- DOC
- Details on study design:
- As per OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
Stammlösung : 2 g/I
Herstellung der Stamrnlösung: 4 g/1800 ml eingewogen; von pH 6,2 auf 6,9 eingestellt; 5 h bei 22°C gerührt; anschließender pH-Wert 6,7. Als klare Lösung abgefüllt.
Analysendaten der Stamrnlösung : DOC 463,5 mg/I [C]
Einsatzkonzentration, als DOC : 202,7 mg/l [C] - Reference substance:
- diethylene glycol
- Remarks:
- 20 g/l in deionised water
- Preliminary study:
- Not assessed
- Test performance:
- The test is considered valid in that the reference substance achieved > 75% degradation in 14 days, as specified by the guideline.
- Parameter:
- % degradation (DOC removal)
- Value:
- < 20
- Sampling time:
- 28 d
- Details on results:
- Ein DOC-Abbau von Reaktiv-Rot F-67787 FW innerhalb des Prüfzeitraumes von 28 Tagen fand nicht statt.
Eine Adsorption an der Biomasse nach 3 Stunden wurde nicht festgestellt.
Die Elimination (Abbau und Adsorption) erreichte 0 %. - Results with reference substance:
- The reference substance achieved > 75% degradation in 14 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- The test substance is deemed not to be inherently biodegradable.
- Executive summary:
The study was conducted via OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test). The results of the study indicated that the substance is not inherently biodegradable.
- Endpoint:
- biodegradation in water: screening test, other
- Remarks:
- COD measurement
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to EU test guidance in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.6 (Degradation: Chemical Oxygen Demand)
- Qualifier:
- according to guideline
- Guideline:
- other: DIN 38 409 part 41
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
None - Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- Stammlösung
Einwaage der Prüfsubstanz: 1000 mg/L
pH-Wert nach Ansatz: 4.6
Der pH wurde nicht korrigiert.
Der Lösungsansatz wurde über 1 Stunde bei 21°C gerührt. Die Einwaage war unter den genannten Bedingungen vollständig löslich. - Reference substance:
- other: Kaliumhydrogenphtalat
- Preliminary study:
- Not conducted.
- Test performance:
- The test was performed in accordance with the parameters specified to meet the requirements.
- Details on results:
- CSB-Bestimmungen der 1 : 10 verdünnten Stammlösung
1. Messung . . .. 66.0992
2. Messung . . . . 64.2114
3. Messung .... 68.7012
Mittelwert x Verdünnungsfaktor: 663 mg[O2]/L
Die Stammlösung enthielt 1 g/l der Prüfsubstanz.
Daraus ergibt sich ein CSB-Wert der Prüfsubstanz von 633 mg[O2]/g - Results with reference substance:
- Referenzsubstanz : Kaliumhydrogenphtalat
Starnmlösung . . . . . . . . . . . . . .. : 170 mg/L in deionisiertem Wasser
berechneter CSB . . . . . . . . . . . .. : 200 mg/L (O2) - Validity criteria fulfilled:
- yes
- Conclusions:
- Chemical oxygen demand: 633 mg[O2]/g
Referenceopen allclose all
Description of key information
Not readily or inherently biodegradable
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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