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Diss Factsheets
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EC number: 266-005-7 | CAS number: 65996-72-7 The dust generated during the charging, operation, and tapping of a steelmaking furnace and from steel conditioning, including that which is recovered through the use of pollution abatement equipment. Composed primarily of iron oxides. May contain varying amounts of other metallic oxides and trace compounds.
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicological Summary
- Administrative data
- Workers - Hazard via inhalation route
- Workers - Hazard via dermal route
- Workers - Hazard for the eyes
- Additional information - workers
- General Population - Hazard via inhalation route
- General Population - Hazard via dermal route
- General Population - Hazard via oral route
- General Population - Hazard for the eyes
- Additional information - General Population
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 5.88 mg/m³
- Most sensitive endpoint:
- effect on fertility
- Route of original study:
- Oral
DNEL related information
- DNEL derivation method:
- ECHA REACH Guidance
- Overall assessment factor (AF):
- 30
- Dose descriptor starting point:
- NOAEL
- Value:
- 100 mg/kg bw/day
- Modified dose descriptor starting point:
- NOAEC
- Value:
- 176.32 mg/m³
- Explanation for the modification of the dose descriptor starting point:
- Inhalation toxicity test is not available.
- AF for dose response relationship:
- 1
- Justification:
- The initial value is NOAEL.
- AF for differences in duration of exposure:
- 6
- Justification:
- The initial end-point is based on Reproduction/Developmental Toxicity Screening Test. Duration exposure in this test is 25-28 days, it means same period as sub-acute test.
- AF for interspecies differences (allometric scaling):
- 1
- Justification:
- Corrected NOAEC was derived for human, it means that interspecies differences are included.
- AF for other interspecies differences:
- 1
- Justification:
- There are not known any information shows specific susceptibility differences between species.
- AF for intraspecies differences:
- 5
- Justification:
- DNEL is derived for workers.
- AF for the quality of the whole database:
- 1
- Justification:
- Reliability of the original study is 1.
- AF for remaining uncertainties:
- 1
- Justification:
- There are not known any information about other uncertainties.
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 0.83 mg/kg bw/day
- Most sensitive endpoint:
- effect on fertility
- Route of original study:
- Oral
DNEL related information
- DNEL derivation method:
- ECHA REACH Guidance
- Overall assessment factor (AF):
- 120
- Dose descriptor starting point:
- NOAEL
- Value:
- 100 mg/kg bw/day
- Modified dose descriptor starting point:
- NOAEL
- Value:
- 100 mg/kg bw/day
- Explanation for the modification of the dose descriptor starting point:
- Dermal toxicity test is not available.
- AF for dose response relationship:
- 1
- Justification:
- The initial value is NOAEL.
- AF for differences in duration of exposure:
- 6
- Justification:
- The initial end-point is based on Reproduction/Developmental Toxicity Screening Test. Duration exposure in this test is 25-28 days, it means same period as sub-acute test.
- AF for interspecies differences (allometric scaling):
- 4
- Justification:
- The test was performed on rats.
- AF for other interspecies differences:
- 1
- Justification:
- There are not known any information shows specific susceptibility differences between species.
- AF for intraspecies differences:
- 5
- Justification:
- DNEL is derived for workers.
- AF for the quality of the whole database:
- 1
- Justification:
- Reliability of the original study is 1.
- AF for remaining uncertainties:
- 1
- Justification:
- There are not known any information about other uncertainties.
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- DNEL (Derived No Effect Level)
- Value:
- 61.28 µg/cm²
- Most sensitive endpoint:
- sensitisation (skin)
DNEL related information
- DNEL derivation method:
- ECHA REACH Guidance
- Overall assessment factor (AF):
- 105
- Dose descriptor:
- other: LOAEL
- Value:
- 6 435 µg/m³
- AF for dose response relationship:
- 3
- Justification:
- The initial value is LOAEL.
- AF for differences in duration of exposure:
- 1
- Justification:
- The test time corresponds to the methodology.
- AF for interspecies differences (allometric scaling):
- 7
- Justification:
- The skin sensitisation test (LLNA) was carried out on mice.
- AF for other interspecies differences:
- 1
- Justification:
- There are not known any information shows specific susceptibility differences between species.
- AF for intraspecies differences:
- 5
- Justification:
- DNEL is derived for workers.
- AF for the quality of the whole database:
- 1
- Justification:
- Reliability of the original study is 1.
- AF for remaining uncertainties:
- 1
- Justification:
- There are not known any information about other uncertainties.
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- medium hazard (no threshold derived)
Additional information - workers
DNEL for dermal and inhalation long-term systemic exposure was derived from Reproduction/Developmental Toxicity Screening Test according to Chapter R.8 Guidance on information requirements and chemical safety assessment. This NOAEL for male fertility seems to be the most sensitive end-point.
DNEL dermal long-term systemic exposure was derived on the basis of Skin sensitisation LLNA test from EC3 value according to Chapter R.8 Guidance on information requirements and chemical safety assessment.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
There are no uses for general population.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.