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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 239-407-5 | CAS number: 15375-84-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
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Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: inherent biodegradability
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well documented study without GLP
Data source
Reference
- Reference Type:
- publication
- Title:
- Chapter 9, Microbial Degradation of EDTA: New EDTA-degrading Bacterial strains
- Author:
- Satroutdinov, A; Chistyakova, T.; Dedyukhina, E. & Minkevich, I.
- Year:
- 2 005
- Bibliographic source:
- Biogeochemistry of chelating agents (eds Nowack, B. and VanBriesen, J.)
Materials and methods
- Principles of method if other than guideline:
- EDTA degrading strains were isolated and incubated to EDTA and EDTA complexes with Mg, Ca, Mn, Zn, Co, Cu and Pb
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Edetic acid
- EC Number:
- 200-449-4
- EC Name:
- Edetic acid
- Cas Number:
- 60-00-4
- Molecular formula:
- C10 H16 N2 O8
- IUPAC Name:
- 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetic acid
- Details on test material:
- no data available
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- not specified
- Duration of test (contact time):
- 24 h
Results and discussion
- Details on results:
- Uncomplexed EDTA and metal-EDTA chelates with low stability constants (log K below 16), such as Mg-, Ca-, Ba-, and Mn-EDTA, were degraded by the washed cell suspensions of both isolates at constant specific rates ranging from 0,310 to 0.525 mmol EDTA/(g cells h). Zn-EDTA with a higher stability constant (log K 18.3) was not completely degraded by resting cell suspensions of Pseudomonas sp, LPM-410 and LPM-4 after an incubation period of 24 h. Initially, the degradation rates of Pseudomonas sp. LPM-410 and LPM-4 were 0.195 and 0.143 mmol EDTA/(g cells h), respectively. After 8 h, degradation rates declined. No degradation of the stable chelates of Pb-, Co-, Cu-EDTA, and Fe(III)-EDTA was observed.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- inherently biodegradable
- Conclusions:
- EDTA-degrading bacterial strains (Pseudomonas sp. LPM-410 and EDTA-dependent strain LPM-4) degraded EDTA and EDTA complexes with Mg, Ca, Mn, and Zn at higher rates (0.143-0.525 mmol EDTA/(g h)), but were unable to degrade EDTA complexes with Co, Cu, and Pb.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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