Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 225-193-0 | CAS number: 4707-47-5
Carcinogenicity
Administrative data
Description of key information
The genotoxicity has been assessed in Ames and in the in vitro micronucleus test and in an in vivo micronucleus test. The substance is negative, positive and negative in these tests, respectively, resulting in absence of genotoxicity.
Key value for chemical safety assessment
Carcinogenicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
Mode of Action Analysis / Human Relevance Framework
Mode of Action is not relevant in absence of adverse effects.
Justification for classification or non-classification
The genotoxicity of the substance has been assessed with three genotoxicity tests. The substance is negative in Ames. The substance is positive in the in vitro micronucleus test but negative in an in vivo micronucleus test. Therefore the substance does not have a genotoxic potential and therefore the substance does not need to be classified for genotoxic carcinogenicity according to EU CLP (EC 1272/2008 and its amendments).
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
