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Diss Factsheets
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EC number: 209-481-3 | CAS number: 582-25-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Study period:
- 48 hours
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- As with all salts, the significance for toxicity or environmental assessment is the presence of specific ions that will form when in solution or when in biological systems. In the case of metal salts of organic acids, the cation is generally critical to determine the solubility in biological or environmental media and if the key physico-chemical properties are equivalent, the potential for hazard and environmental fate will be equivalent.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- Continued over 96 hours
- Principles of method if other than guideline:
- 96 hour LC50 values on a number of species
- GLP compliance:
- no
- Specific details on test material used for the study:
- Not specified
- Analytical monitoring:
- not specified
- Vehicle:
- no
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- All test organismswere acclimated to the control diluent and food was witheld for 24h prior to the start of the test. Juveniles of each species were used for the test (10 per species per treatment). Biological loading was kept below 0.5g wet weight per litre test solution.
- Test type:
- static
- Water media type:
- freshwater
- Remarks:
- Lake Ontario- fully characterised media
- Limit test:
- no
- Total exposure duration:
- 96 h
- Remarks on exposure duration:
- Considered valid for classification and to establish read-across potential
- Hardness:
- 130 mg/L
- Test temperature:
- 20 C
- pH:
- 6.5 - 8.0
Media : 7.4 - Dissolved oxygen:
- If the dissolved oxygen concentration in a test chamber fell below 40% of the starting level in a test, the test was repeated with 0.05 L/min glass-sparger aeration.
- Conductivity:
- 260 umhos/cm
- Reference substance (positive control):
- no
- Key result
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- not specified
- Conclusions:
- Considered valid for classification and to establish read-across potential
- Executive summary:
This study is cited in UN Concise International Chemical Assessment Document 26 on Sodium Benzoate and other references confirm low toxicity to Daphnia and other invertebrates
Reference
Description of key information
Reported EC50 > 100 mg/l for Sodium benzoate
Reported EC50 > 100 mg/l for Benzoic acid
The read-across document for ecotoxicity is integral to the endpoint, as is the overall read-across justification document.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Both values are cited in the respective REACh Registration dossiers. In addition, a publication is available for Sodium benzoate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.