Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
235-183-8
CAS no.:
12124-97-9
Index number:
Molecular formula:
BrH4N
SMILES:
[NH4+].[Br-]
InChI:
InChI=1S/BrH.H3N/h1H;1H3
Type of substance:
Mono constituent substance
Origin:
Inorganic
Registered compositions:
2
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Warning! According to the classification provided by companies to ECHA in REACH registrations this substance causes serious eye irritation.

Additionally, the classification provided by companies to ECHA in CLP notifications identifies that this substance causes skin irritation and may cause respiratory irritation.

Breakdown of all 967 C&L notifications submitted to ECHA

Eye Irrit. 2 H319
Skin Irrit. 2 H315
STOT SE 3 H335
Not Classified
Eye Irrit. 2A H319
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

Regulatory activities

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 2 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Substance Evaluation:
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Classification Labelling & Packaging (CLP)

Harmonised C&L:
Notification:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
This substance is approved for use as a Biocidal Active Substance
Biocidal Products:
There are 0 authorised Biocidal Product(s) that use this substance as an active ingredient

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is manufactured and/or imported in the European Economic Area in 1 000 - 10 000 tonnes per year.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing and at industrial sites.

This substance is being reviewed for use as a biocide in the EEA and/or Switzerland, for: preservation for liquid systems, controlling slimes.

This substance is used in the following products: photo-chemicals.

Other release to the environment of this substance is likely to occur from: indoor use and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal) and in the production of articles. Other release to the environment of this substance is likely to occur from: indoor use and outdoor use in long-life materials with high release rate (e.g. tyres, treated wooden products, treated textile and fabric, brake pads in trucks or cars, sanding of buildings (bridges, facades) or vehicles (ships)).

This substance can be found in products with material based on: wood (e.g. floors, furniture, toys) and fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys).

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following areas: formulation of mixtures and/or re-packaging.

This substance is used in the following activities or processes at workplace: roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of chemicals at non-dedicated facilities, transfer of substance into small containers, the low energy manipulation of substances bound in materials or articles and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: formulation of mixtures and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal). Other release to the environment of this substance is likely to occur from: indoor use.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

This substance is used in the following activities or processes at workplace: closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of chemicals at non-dedicated facilities, transfer of substance into small containers and production of mixtures or articles by tabletting, compression, extrusion or pelletisation.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: pharmaceuticals.

This substance is used for the manufacture of: chemicals.

This substance is used in the following activities or processes at workplace: the low energy manipulation of substances bound in materials or articles, industrial spraying, roller or brushing applications, treatment of articles by dipping and pouring, closed batch processing in synthesis or formulation, mixing in open batch processes, transfer of chemicals at non-dedicated facilities, transfer of substance into small containers, production of mixtures or articles by tabletting, compression, extrusion or pelletisation, lubrication at high energy conditions and in partly open process and high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding).

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates) and industrial abrasion processing with low release rate (e.g. cutting of textile, cutting, machining or grinding of metal).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier.

Response statements

In case of incident: If in eyes: rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing. If eye irritation persists get medical advice/attention.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • ICL- IP Terneuzen B.V., Frankrijkweg 6 Havens/Docks 1205-45308 BJ 4538 BJ Terneuzen Netherlands
  • ICL-IP Terneuzen B.V. (OR2), Frankrijkweg 6 Havens/Docks 1205-45308 4538 BJ Terneuzen Netherlands

Substance names and other identifiers

Ammonium bromide
EC Inventory, REACH pre-registration
Bromide activated chloramine (BAC) generated from ammonium bromide and sodium hypochlorite
Biocidal active substances
Ammonium bromide ((NH4)Br)
Other
Ammonium, bromide
C&L Inventory
Ammoniumbromid
C&L Inventory
azane hydrobromide
C&L Inventory
Bromure d’ammonium
C&L Inventory
101215-76-3
Deleted CAS number
Other
12124-97-9
CAS number
EC Inventory, C&L Inventory, Biocidal active substances, Registration dossier, REACH pre-registration, Other
14216-86-5
Deleted CAS number
Other
204322-88-3
Deleted CAS number
Other
252189-56-3
Deleted CAS number
Other
357290-88-1
Deleted CAS number
Other
7789-32-4
Deleted CAS number
Other
80209-35-4
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Solid (100%) [1]
C Form
Crystalline (100%) [1]
C Odour
Odourless (100%) [1]
C Substance type
Inorganic (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Solid (100%)

Melting/freezing point

Study results
  • 2 studies submitted
  • 1 study processed
R Melting / freezing point
370 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
370 °C

Boiling point

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Density

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
2.455

Vapour pressure

Study results
  • 1 study submitted
  • 1 study processed
R Vapour pressure
0 Pa @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
0 Pa @ 25 °C

Partition coefficient

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-1 @ 25 °C

Water solubility

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
10 g/L @ 25 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 1 study processed
R Surface tension
72.9 mN/m @ 400 mg/L and 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Surface tension at 20 °C
72.9 mN/m @ 400 mg/L

Flash point

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Auto flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Non flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 1 study processed
C Interpretation of results
Non-explosive (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
9.384 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
pKa at 20 °C
9.384

Viscosity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Data not provided by the registrant

Hydrolysis

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Bioaccumulation Factor (BCF) - dimensionless
0.23

Bioaccumulation: terrestrial

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Adsorption/desorption

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
0.1

Henrys law constant (H)

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Henry's law constant
0 Pa.m³.mol-1 @ 25 °C

Distribution modelling

Data not provided by the registrant

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 520 µg/L (1)
Intermittent releases (freshwater) 109 mg/L (1)
Marine water 41 mg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 100 mg/L (1)
Sediment (freshwater) No exposure of sediment expected (1)
Sediment (marine water) No exposure of sediment expected (1)
Hazard for Air
Air -
Hazard for Terrestrial Organism
Soil 3.2 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 12 studies submitted
  • 3 studies processed
P/RResults
LC50 (4 days) 440 - 1 000 mg/L [2]
NOEC (4 days) 320 - 1 000 mg/L [3]

Type of Study provided
Studies with data
Key study 3
Supporting study 9
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
LC50 for freshwater fish
440 mg/L

Long–term toxicity to fish

Study results
  • 11 studies submitted
  • 1 study processed
P/RResults
NOEC (4.133 months) 10 mg/L [1]
LOEC (4.133 months) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 10
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater fish
10 mg/L

Short–term toxicity to aquatic invertebrates

Study results
  • 12 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 1 g/L [1]
NOEC (48 h) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 11
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 / LC50 for freshwater invertebrates
1 g/L

Long–term toxicity to aquatic invertebrates

Study results
  • 14 studies submitted
  • 2 studies processed
P/RResults
NOEC (21 days) 7.5 mg/L [1]
NOEC (16 days) 2.8 mg/L [1]
LOEC (21 days) 19 mg/L [1]
LOEC (16 days) 5 mg/L [1]
EC10 (16 days) 43 mg/L [1]

Type of Study provided
Studies with data
Key study 2
Supporting study 12
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 / LC10 or NOEC for freshwater invertebrates
2.8 mg/L

Toxicity to aquatic algae and cyanobacteria

Study results
  • 8 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 440 mg/L [1]
NOEC (72 h) 440 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for marine water algae
440 mg/L
EC10 or NOEC for freshwater algae
3.2 g/L

Toxicity to aquatic plants other than algae

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for freshwater plants
3.2 g/L

Toxicity to microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (3 h) 1.739 g/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for microorganisms
1 g/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 2 studies submitted
  • 2 studies processed
P/RResults
NOEC (56 days) 32 mg/kg soil dw [1]
NOEC (14 days) 10 mg/kg soil dw [1]
EC50 (56 days) 53 mg/kg soil dw [1]
EC50 (14 days) 1 g/kg soil dw [1]
LC50 (28 days) 92.9 mg/kg soil dw [1]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg soil dw
Long-term EC10 / LC10 / NOEC
32 mg/kg soil dw

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / LC10 / NOEC
100 mg/kg soil dw

Toxicity to terrestrial plants

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 180 - 1 000 mg/kg soil dw [3]
EC50 (21 days) 1 g/kg soil dw [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
1 g/kg soil dw
Long-term EC10 / LC10 / NOEC
180 mg/kg soil dw

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (28 days) 1 g/kg soil dw [1]
EC50 (28 days) 1 g/kg soil dw [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Long-term EC10 / NOEC
1 g/kg soil dw

Toxicity to birds

Study results
  • 4 studies submitted
  • 3 studies processed
P/RResults
NOEC (14 days) 292 mg/kg bw [1]
LC50 (21 days) 2 150 mg/kg bw [1]
LC50 (14 days) 2 250 mg/kg bw [1]
LC50 (5 days) 5 633 mg/kg diet [1]

Type of Study provided
Studies with data
Key study 4
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Short-term EC50 / LC50
5.633 g/kg food

Toxicity to mammals

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 4.75 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 95 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 95 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
EYE Exposure
-
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.66 mg/m³ repeated dose toxicity
Acute /short term: - -
Local Effects
Long-term: - -
Acute /short term: - -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 95 mg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 95 mg/kg bw/day repeated dose toxicity
Local Effects
Long-term: - -
Acute /short term: - -
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 475 µg/kg bw/day repeated dose toxicity
Acute /short term: (DNEL) 27 mg/kg bw/day acute toxicity
EYE Exposure
-

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 32 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 5 1
Supporting study 26
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study 3
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 3 summaries submitted
  • 2 summaries processed
Bioaccumulation potential:
Low bioaccumulation potential
Absorption values
Dermal: 1 %

Acute toxicity

Study results
oral
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 566 - 2 868 mg/kg bw (rat) [3]
M/CInterpretations of results
Not classified [1]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 h) 100 mg/m³ air (rat) [1]
M/CInterpretations of results
Not classified [1]

inhalation
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
dermal
  • 2 studies submitted
  • 1 study processed
P/RResults
LD50 2 000 mg/kg bw (rat) [1]
M/CInterpretations of results
Not classified [1]

dermal
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Irritation / corrosion

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
No adverse effect observed (not irritating)
Eye
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 13 studies submitted
  • 2 studies processed
P/RResults
NOAEL (rat): 100 mg/kg bw/day [1]
NOAEL (rat): 300 mg/kg diet [1]
LOAEL (rat): 100 - 225 mg/kg bw/day [2]

Type of Study provided
Study data: oral
Studies with data
Key study 3
Supporting study 9 1
Weight of evidence
Other
Data waiving
no waivers
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Genetic toxicity

Study results
Study data: in vitro
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Carcinogenicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to reproduction

Study results
Study data: reproduction
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 2
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Neurotoxicity

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 7
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant