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EC number: 309-831-6 | CAS number: 101227-08-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- expermimental period: January 19th - 21st 2005
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTIONS
- Method: stirring 100.2 mg/l of the test item in Daphnia dilution water according to OECD 202 for 24 hours followed by filtration with a 0.45 µm CA-filter (cellulose acetate syringe filter, Schleicher&Schuell PP 30/0.45 C); the water soluble fraction (WSF) was tested
- Controls: Daphnia dilution water according to OECD 202 - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- TEST ORGANISM:
- Common name: Daphnia magna Straus
- Source: German Federal Environment Agency,
the current breeding was held at Hydrotox GmbH since October 2001; Twice a week the animals are placed into fresh Elendt-Medium M4 (acc. OECD 202). They are kept at approximately 10 animals/200 ml; five days a week they are fed with a suspension of the green algae Desmodesmus subspicatus; During the test Dapnia were not fed.
ACCLIMATION
Daphnia are held at 20 +/- 1°C with a light dark cycle of 12:12 h; the breeding was stable since August 1999; the test was performed under the same conditions but in the dark - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Post exposure observation period:
- non
- Hardness:
- not determined
- Test temperature:
- 20-21°C
- pH:
- control: 7.7 (0h) and 7.6 (48h)
100 mg/l: 7.7 (0h) and 7.7 (48h) - Dissolved oxygen:
- control: 0h - 8.8 and 48h - 8.7 mg/L
100 mg/l: 0h - 8.8 and 48 h - 8.8 mg/L - Nominal and measured concentrations:
- nominal concentration: 100.2 mg/l (nominal loading rate)
- Details on test conditions:
- TEST SYSTEM
- Test vessel:
- glass beaker 50 ml filled with a test volume of 20 ml; no aeration
- no renewal of test solution during the test duration of 48 hours
- 5 Dapnia per vessel
- 4 replicate vessels per concentration and control
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Dilution water according to OECD 202;
- Culture medium different from test medium: yes, culture medium: Elendt-Medium M4 according to OECD 202
- Intervals of water quality measurement: conductivity of the deionised water used for the preparation of the culture medium and the dilution water is measured dayly
OTHER TEST CONDITIONS
- Adjustment of pH: pH of the test solution was not adjusted
- Photoperiod: the test was performed in the dark
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) :
After 24 and 48 hours the test vessels were taken out from the incubator and put onto a black cloth, and the swimming capability of the Daphnia was observed. An animal that did not swimm within 15 seconds after gently moving the beaker was considered to be immobile.
TEST CONCENTRATIONS
the test was performed as Limit test with a test concentration of 100.2 mg/l - Reference substance (positive control):
- yes
- Remarks:
- Potassium dichromate
- Duration:
- 24 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mobility
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- dissolved
- Basis for effect:
- mobility
- Details on results:
- No effect on the swimming capability (mobility) of Dapnia with the water soluble fraction (WSF). The EL50 > 100.2 mg/l. The test was performed without accompanying chemical analysis due to the insoluble nature of the test item.
- Results with reference substance (positive control):
- EC50 for the reference substance potassium dichromate determined in September 2004; results are not given in the report
- Validity criteria fulfilled:
- yes
- Conclusions:
- The study was performed as limit test with the water soluble fraction (WSF) after 24 hours stirring and filtration and a nominal test concentration of
100.2 mg/l. No effects on the swimming capability of the Daphnia could be observed. The EL50 (48 h) is > 100.2 mg/L - Executive summary:
The study was performed as limit test with the water soluble fraction (WSF) after 24 hours stirring and filtration and a nominal test concentration of 100.2 mg/l. No effects on the mobility of the Daphnia could be observed. The EC50 (48 h) is > 100.2 mg/L.
Reference
Description of key information
In a well conducted OECD 202 study with the target substance Fatty acids, C16-18, 2-butyloctyl esters the EL50 (48 h) is > 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
An OECD 202 test was performed with the target substance Fatty acids, C16-18, 2-butyloctyl esters as limit test with the water soluble fraction (WSF) after 24 hours stirring and filtration and a nominal test concentration of 100.2 mg/l. No effects on the mobility of the Daphnia could be observed. The EL50 (48 h) is > 100.2 mg/L.
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