Registration Dossier
Registration Dossier
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EC number: 225-083-2 | CAS number: 4651-67-6
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Study period:
- Last Revision Date: 1992/12/15
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
Data source
Reference
- Reference Type:
- other: Secondary source
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Results and discussion
Test resultsopen allclose all
- Key result
- Species / strain:
- S. typhimurium TA 98
- Metabolic activation:
- without
- Genotoxicity:
- negative
- Key result
- Species / strain:
- S. typhimurium TA 100
- Metabolic activation:
- without
- Genotoxicity:
- negative
- Key result
- Species / strain:
- S. typhimurium TA 98
- Metabolic activation:
- with
- Genotoxicity:
- negative
Applicant's summary and conclusion
- Conclusions:
- Ames test performed on Salmonella Typhimurium (strains TA98, TA100) was both negative with both metabolic activation and without.
- Executive summary:
Available data are inconclusive for the assessment of the germ cell mutagenicity of the substance.
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