Registration Dossier
Registration Dossier
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EC number: 811-616-1 | CAS number: 1563063-07-9
Endpoint summary
Administrative data
Description of key information
Oral (OECD 423), rat: LD50 cut-off = 2000 mg/kg bw
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
The acute oral toxicity of the test substance was assessed in a study according to OECD Guideline 423 and in compliance with GLP (2016). In step 1, the test substance was administered via oral gavage to 3 female rats at dose level of 2000 mg/kg bw. Since no mortality occurred, 2000 mg/kg bw was administered to 3 further animals in a second step. One animal was found dead each on Day 2 and 3 after administration. Therefore, 300 mg/kg bw was administered to 3 animals each in step 3 and 4. No mortality was observed at 300 mg/kg bw. Based on the results a LD50 cut-off of 2000 mg/kg bw was determined in this study.
Justification for classification or non-classification
The available data on acute oral toxicity of the test substance meet the criteria for Acute Tox. Cat 4 (H302) according to Regulation (EC) No 1272/2008.
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