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Diss Factsheets
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EC number: 943-265-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_environmental-fate-and-pathways.png)
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- May 2014 - July 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- other:
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Batch No.of test material: 3706OB
- Expiration date of the lot/batch: 3MArch 2019
- Purity test date: March 2014
- Purity: 99%
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: room temperature in the dark - Radiolabelling:
- no
- Key result
- Sample No.:
- #1
- Type:
- log Koc
- Value:
- 3.21 dimensionless
- Matrix:
- Bisphenol AF
- Key result
- Sample No.:
- #2
- Type:
- log Koc
- Value:
- 6.59 dimensionless
- Matrix:
- Phosphonium Salt
- Details on results (HPLC method):
- The estimated results for the Phosphonium Ion are log10 Koc 6.59 and Koc 3.90 x 10E6
- Validity criteria fulfilled:
- yes
- Conclusions:
- - for the Bisphenol AF: Koc was determined using the HPLC method, Log Koc was 3.21 leading to a mobility class of " low mobility"
- for the Phosphonium Salt: Koc was predicted using structural analysis (calculation), Log Koc was 6.59 leading to a mobility class of "immobile" - Executive summary:
The adsorption coefficient has been determined using the HPLC screening method, designed to be compatible with Method C19 Adsorption Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001.
The test item has two components Bisphenol AF and a Phosphonium counterion. The Bisphenol AF has an estimated dissociation constant of 8.7 to 9.5 and is therefore ‘seen’ by the HPLC analysis required for adsorption coefficient. The Phosphonium Salt however, at pH 7, is a cationic substance and can bind to the HPLC stationary phase, due to secondary ionic interactions with the residual silianol groups of the HPLC column, therefore a calculation was considered more appropriate.
The results are as follows:
- for the Bisphenol AF: Log Koc was 3.21 leading to a mobility class of " low mobility"
- for the Phosphonium Salt: Log Koc was 6.59 leading to a mobility class of "immobile"
Reference
The test item has two components Bisphenol AF and a Phosphonium counterion. The Bisphenol AF has an estimated dissociation constant of 8.7 to 9.5 and is therefore ‘seen’ by the HPLC analysis required for adsorption coefficient. The Phosphonium Salt however, at pH 7, is a cationic substance and can bind to the HPLC stationary phase, due to secondary ionic interactions with the residual silianol groups of the HPLC column, therefore a calculation was considered more appropriate.
Description of key information
The partition coefficient was determined using the flask method, designed to be compatible with Method A8 Partition Coefficient of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 107 of the OECD Guidelines for Testing of Chemicals, 27 July 1995. No deviation from the guideline has been observed during the test.
The test item has two components Bisphenol AF and a Phosphonium counterion. The Bisphenol AF has an estimated dissociation constant of 8.7 to 9.5 and is therefore ‘seen’ by the HPLC analysis required for adsorption coefficient. The Phosphonium Salt however, at pH 7, is a cationic substance and can bind to the HPLC stationary phase, due to secondary ionic interactions with the residual silianol groups of the HPLC column, therefore a calculation was considered more appropriate.
The results are as follows:
- for the Bisphenol AF: Log Koc was 3.21
- for the Phosphonium Salt: Log Koc was 6.59
Key value for chemical safety assessment
- Koc at 20 °C:
- 3 900 000
Additional information
For the Risk assessment, a conservative approach is applied i.e. the log Koc of the component with the lowest log Koc was used.
[LogKoc: 6.59]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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