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EC number: 242-538-0 | CAS number: 18727-04-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 (72 h) = 1.6 mg cobalt citrate/L (Desmodesmus subspicatus) (equivalent to 2.15 mg cobalt hydrogencitrate/L )
NOECr (72 h) = 0.11 mg cobalt citrate/L (Desmodesmus subspicatus) (equivalent to 0.15 mg cobalt hydrogencitrate/L)
LC50 (96h) = 2.52 mg cobalt hydrogencitrate/L (Chlorella vulgaris) (read-across from cobalt chloride)
LC50 (96h) = 1.26 mg cobalt hydrogencitrate/L (Ditylum brightwellii) (read-across from cobalt chloride)
NOEC (21d) = 2.52 mg cobalt hydrogencitrate/L (Chlorella vulgaris) (read-across from cobalt nitrate)
Key value for chemical safety assessment
Additional information
One study on the toxicity to algae is available for cobalt citrate (CAS 866-81-9). Within this key study conducted according to OECD 201 and GLP, Desmodesmus subspicatus was exposed to 0.1, 0.22, 0.46, 1.0 and 2.2 mg/L test substance (nominal) for 72 h under static exposure (Muckle, 2012). As a result, an EC50 of 1.6 mg/L, equivalent to 2.15 mg cobalt hydrogencitrate/L and a NOEC of 0.11 mg/L, equivalent to 0.15 mg cobalt hydrogencitrate/L were reported for growth rate. Analytical measurements showed recoveries of 35 to 92%, thus the results were based on measured concentrations (geometric mean).
Additionally, there are reliable data available for different analogue cobalt compounds.
Data on algae toxicity tests resulting in high quality EC50 values (expressed as Co) for freshwater algae and protozoans (n=10) are summarised in Table 2 of the WHO CICAD document, 2006 (see attached document).Acute and chronic data for different algae species in fresh- and saltwater were extracted and used in the effects assessment.
The EC50 values for freshwater algae range from 0.56 mg Co/L for Chlorella vulgaris (Rachlin and Grosso, 1993) to 10.8 mg Co/L for Spirulina platensis (WHO CICAD, 2006). Two EC50 values were available for marine species with a similar spectrum of 0.3 mg Co/L for Ditylum brightwellii and 10.2 mg Co/L for Nitzschia closterium. The 21-day NOECs and LOECs for freshwater algae ranged from 0.6 to 1.6 mg Co/L (WHO CICAD, 2006).
These findings result in recalculated values from 2.37 to 45.6 mg cobalt hydrogencitrate/L for acute freshwater endpoints, from 1.27 to 43.1 mg cobalt hydrogencitrate/L for acute marine endpoints and from 2.5 to 6.8 mg cobalt hydrogencitrate/L for chronic freshwater endpoints.
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