Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 830-086-2 | CAS number: 742087-48-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 48 hours
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Justification for type of information:
- SugaNate 160NC has been used in this end point as a read-across substance for SugaNate 100NC. A comparison of the two substances and a read-across justification can be found in section 13 of this dataset.
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Version / remarks:
- Chinese GLP equivalent method
- Deviations:
- not applicable
- Principles of method if other than guideline:
- The objective of the study was to assess acute toxicity of the test item towards Daphnia magna (Daphnia magna Straus) under semi-static exposure procedure. The nominal concentrations of test item was 4.0,6.0,8.9. 13.4 and 20.0 mg/L, and blank control was set in parallel" Four replicates was set in each group and five daphnids were used in each replicate. The test duration lasted for 48 hours. lmmobilization was observed at 24 h and 48 h of exposure. The EC5s and its 95% confidence limits was calculated.
The test item is a UVCB substance, the change of the test item was monitored by total organic carbon (TOC) analysis during the test. The samples of the test item treatment groups and blank control group were taken to determine the TOC concentration at the beginning of exposure (0h), at the end of exposure (48h) and 24 hours before and after test solution renewal. - GLP compliance:
- yes
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Remarks:
- water
- Details on test solutions:
- Based on the result of the preliminary test, the nominal concentrations of the test item were 4.0, 6.0, 8.9, 13.4 and 20.0 mgil in the definitive test.
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Test system: Daphnia magna Straus
Source: The species Daphnia magna was originally supplied by Shenyang Research Institute of Chemical Industry. The clone has been breeding in CTI-SET.
Result of sensitivity lest: The result of the latest sensitivity test (Study No.:17ST003) conducted from 03 March 2017 to 05 March 2017 indicated that the 24h-EC5s of potassium bichromate (CAS No.: 7778-5A-q b Daphnia magna Straus was 1.0 mg/L and its 95%
confidential limit was 0.9-1.1 mg/L, which satisfied the requirement recommended by ISO 6341-2412 ffhe 24h-E0so of potassium bichromate ta Daphnia magna Straus was in the range of 0.6-2.1 rng/L).
Acclimation: the tap water dechlorinated by aeration was used to maintain the stock anirnals. During the acclimation, the temperature was controlled between 18-22oC, the pH values were 6-9, the oxygen concentration was above 3 mg/L. The test water were
inconsistent with that used in the culture, therefore the brood daphnids were maintained in test water under the test condition for 48 hours prior to the test. The test organisms were less than 24 hours old and the third brood progeny. They were derived from a healthy stock {the internal number of parent daphnids was Daphnia magna Q2017A6AT). - Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Hardness:
- The hardness of test waterwas 240 mg /L (Calculate as CaCOa)
- Test temperature:
- The temperature of the test water was maintained at 20.67-20.91"C.
- pH:
- the pH value of test sofution was 7.71-8.04.
- Dissolved oxygen:
- During the period of the exposure, the dissolved oxygen was in the range of 8.53 - 8.80 mg/L
- Nominal and measured concentrations:
- The change of the test ilem was monitored by TOC analysis during the test. The TOC concentrations of test solution test item treatment groups and control group were determined at the beginning of exposure (0h), at the end of exposure (4Sh) and 24 hours before and after test solution renewal.
During the test, except the group of 4.0 mgll, the measured TOC concentration of test item in the solution was maintained in the range of 88%-104% of initial measured concentration, which was in the range of 80%-120%. The measured TOC concentration of test solution in the group of 4.0 mg/L was 62%-76% of initial measured concentration. lt was refened that the measured TOC concentration of 4.0 mg/L was low, which was in the range of 0.5 - 1.0 mg/L), and the TOC concentration of blank control solution was near the limit of detection (0.5 mg/L). Corrected by blank, the calculated TOC concentration of test item had a big fluctuation and the result did not indicate that the TOC concentration of test item could not be maintained during the test. Therefore, the effect concentration could be calculated based on the nominal concentration. - Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 12.9 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Details on results:
- Based on the nominal concentrations, the 48h-EC50 of the test item to Daphnia magna was cafculated to be 12.9 mg/L and its 95% confidence limits was 11.4 - 14.7 mg/L.
- Validity criteria fulfilled:
- yes
- Executive summary:
The objective of the study was to assess acute toxicity of the test item towards Daphnia magna (Daphnia magna Straus) under semi-static exposure procedure. The nominal concentrations of test item was 4.0,6.0,8.9. 13.4 and 20.0 mg/L, and blank control was set in parallel" Four replicates was set in each group and five daphnids were used in each replicate. The test duration lasted for 48 hours. lmmobilization was observed at 24 h
and 48 h of exposure. The EC50 and its 95% confidence limits was calculated.
Corrected by blank, the calculated TOC concentration of test item had a big fluctuation and the result did not indicate that the TOC concentration of test item could not be maintained during the test. Therefore, the efiect concentration could be calculated based on the nominal concentration.
Based on the nominal concentrations, the 48h-EC50 of the test item to Daphnia Magna was calculated to be 12.9 mg/L and its 95% confidence limits was 11.4-14.7 mg/L.
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Justification for type of information:
- SugaNate 160NC has been used in this end point as a read-across substance for SugaNate 100NC. A comparison of the two substances and a read-across justification can be found in section 13 of this dataset.
- Qualifier:
- according to guideline
- Guideline:
- other: ESA SOP 101 based on USEPA (2002)
- Deviations:
- no
- GLP compliance:
- yes
- Test organisms (species):
- Ceriodaphnia sp.
- Test type:
- static
- Water media type:
- not specified
- Total exposure duration:
- 48 h
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 16.3 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks:
- 0%
- Conclusions:
- EC50(48H) = 16.3 mg/l
NOEC= 10mg/l
LOEC=20mg/l - Executive summary:
48h Acute (survival) toxicity test using the freshwater cladoceran (Ceriodaphnia of dubia)
Method: ESA SOP 101 , based on USEPA (2002)
No deviation
Test temperature 25 +/- 1ªC
Test performed under GLP Principles by ECOTOX Services Australia
NOEC: 10 mg/l
Referenceopen allclose all
Description of key information
Based on the nominal concentrations, the 48h-EC50 of the test item to Daphnia Magna was calculated to be 12.9 mg/L and its 95% confidence limits was 11.4-14.7 mg/l, based on immobility
In addition, 48h Acute (survival) toxicity test using the freshwater cladoceran (Ceriodaphnia of dubia) gave a value of 16.3 mg/l, based on mortality
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 12.9 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.