Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-207-4 | CAS number: 10595-80-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Jun 2019
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Batch No. 0066758
- Analytical monitoring:
- yes
- Details on sampling:
- At least duplicate samples from the freshly prepared test media of the only test concentration and the control will be taken.
For the determination of the stability of the test item under the test conditions and of the maintenance of the test item concentration during the test period, the concentration in the test vessels will be sampled at least in duplicate at the end of the test (after the 48 hours test period).
All samples will be diluted by a factor of 2 with acetonitrile.
Additional samples of the control and the dilution solvent will be taken at each sampling without any sample treatment. - Vehicle:
- no
- Details on test solutions:
- The only test item concentration will be nominal 100 mg test item/L. Additionally; a control will be tested in parallel (test water without addition of the test item). Thus a limit test will be performed in accordance with OECD Guideline 202 to demonstrate that the test item has no toxic effect on the test animals up to this concentration.
In the control, test water will be used without addition of the test item.
Before test initiation, the test medium of the only test concentration of nominal 100 mg test item/L will be prepared. The test item will be dissolved or dispersed into the test water as homogeneously as possible.
The test medium will be prepared just before introduction of the daphnids (= start of the test). - Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Species: Daphnia magna (Straus), clone 5
Age at Test Start: Less than 24 hours old
Origin: The daphnids introduced in the test will be taken from ibacon's in-house laboratory culture.
Breeding Conditions: The daphnids are bred in the laboratories of ibacon under similar temperature and light conditions as used in the test. The cultivation of the parental daphnids is performed in Elendt M4 medium. The test organisms will not be first brood progeny. The daphnids in the stock culture are fed at least on all working days with green algae (Desmodesmus subspicatus) freshly grown in the laboratories of ibacon.
Reference Item: For the evaluation of the quality of the Daphnia clone and the consistency of the experimental conditions, the reference item potassium dichromate is tested at least twice a year to demonstrate satisfactory test conditions.
Acclimatisation: Is not necessary since the breeding is performed in the same water. - Test type:
- static
- Water media type:
- other: Reconstitued Water (Elendt "M4")
- Limit test:
- yes
- Total exposure duration:
- 48 h
- Hardness:
- Calculated Water hardness: 2.5 mmol/L (= 250 mg/L) as CaCO3
- Test temperature:
- 18 °C - 22 °C with a maximum deviation of ± 1 °C within this range.
- pH:
- pH 6 – 9
- Dissolved oxygen:
- >3 mg/L
- Salinity:
- Calculated Alkalinity: 0.9 mmol/L
- Details on test conditions:
- 1.1 Test Conditions
Test Environment: Controlled environment room
Measurement of pH, Dissolved Oxygen and Water Temperature:
The water temperature, pH-values and dissolved oxygen concentrations will be determined at test start and test end in each treatment group.
pH-Value of Test Medium: pH 6 – 9
Dissolved Oxygen Concentration: 3 mg/L
Water Temperature: 18 °C - 22 °C with a maximum deviation of ± 1 °C within this range.
Measurement of Light Intensity: The light intensity will be measured at least once during the test.
Light Regime: 16 h light : 8 h dark
Light Intensity: Not exceeding 1500 lux
Recording: Test conditions will be recorded with suitable instruments and documented in the raw data. - Reference substance (positive control):
- yes
- Remarks:
- Control: Reconstituted water
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Validity criteria fulfilled:
- yes
- Conclusions:
- The toxic effect of the test item 2-SEM to Daphnia magna was assessed in a static limit test. The 48-hour EC50 value was calculated to be >100 mg test item/L.
The initial concentrations and the maintenance of the exposure concentrations during the test were verified in the analytical part.
Reference
Description of key information
The toxic effect of the test item 2-SEM to Daphnia magna was assessed in a static limit test. The 48-hour EC50 value was calculated to be >100 mg test item/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.