Registration Dossier
Registration Dossier
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EC number: 228-589-1 | CAS number: 6300-50-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The short-term toxicity to algae is determined by read-across to the structural analogue substance Direct Red 254 TEA salt (CAS 64683-40 -5). One test conducted according to the OECD Guideline 201 (Alga, Growth Inhibition Test) on the structural analogue substance resulted on one EC50>100 mg/L, and at the maximum concentration tested no deaths were observed. Considering the existing information, the substance is classified as not harmful to algae and cyanobacteria.
There is one study available to determine the short-term toxicity of the substance Direct Red 254 sodium salt (CAS 6300 -50 -1) to Daphnia according to OECD Guideline 202.At the maximum concentration tested (EC50(daphnia)>200 mg/L act. ingr.) and considering the existing information, the substance is not harmful to aquatic invertebrates.
There are two additional studies conducted on the structural analogue substance Direct Red 254 TEA salt (CAS 64683-40 -5). TheEC50 (48h) values are 155 mg/L active ingr. and 175 mg/L active ingr. respectively, show that the tested substance is not harmful to aquatic invertebrates.
The tested substances have identical structure in respect to the anionic constituents.
The results of all the studies support the effect of the substance to aquatic invertebrates and the read-across approach between both structures.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 115 mg/L
Additional information
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