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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

Oncorhynchus mykiss did not bioaccumulate TiO2 particles in the inner organs during the 14-d exposure at concentrations up to 1 mg/L. 
These data are used in a read-across approach for TiC. For details please refer to the read-across report.

Key value for chemical safety assessment

Additional information

No data on bioaccumulation or levels of titanium carbide in aquatic organisms are available. However, bioaccumulation/bioconcentration data of titanium dioxide are available (Frederici et al., 2007). 14-day exposure of Oncorhynchus mykiss to TiO2 at aqueous concentrations of 0 (control), 0.1, 0.5, and 1.0 mg/L did not lead to significant accumulation in tissues (gills, liver, muscle, and brain) compared to the control. Thus, it can be concluded that fish did not bioaccumulate TiO2 particles in the inner organs during the 14-d exposure.