Registration Dossier
Registration Dossier
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EC number: 232-197-6 | CAS number: 7790-28-5
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- in vivo insect germ cell study: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- not reported
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Data from a report from a recognised body reviewed by a panel of experts. Although there is limited detail on materials and methods included in the publication, the conclusions drawn from the cicads document are considered to be reliable and representative of the mutagenic potential of the substance.
Cross-reference
- Reason / purpose for cross-reference:
- other: read across: target
Reference
- Endpoint:
- in vivo insect germ cell study: gene mutation
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reason / purpose for cross-reference:
- read-across source
- Additional information on results:
- Sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila.
- Conclusions:
- Interpretation of results: negative
The publication reported that sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila. No information is provided on experimental materials and methods. - Executive summary:
The publication reported that sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila. No information is provided on experimental materials and methods.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Final Report on the Safety Assessment of Sodium Iodate
- Author:
- International Journal of Toxicology
- Year:
- 1 995
- Bibliographic source:
- http://ijt.sageub.com/content/14/3/231
- Reference Type:
- other: report from a recognised body
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- GLP compliance:
- not specified
- Type of assay:
- Drosophila SLRL assay
Test material
- Reference substance name:
- Sodium iodate
- EC Number:
- 231-672-5
- EC Name:
- Sodium iodate
- Cas Number:
- 7681-55-2
- IUPAC Name:
- sodium iodate
- Test material form:
- solid: crystalline
- Details on test material:
- - Name of test material (as cited in study report): sodium iodate
- Appearance: white crystalline solid
Constituent 1
Test animals
- Species:
- Drosophila melanogaster
- Details on test animals or test system and environmental conditions:
- No further information provided on test animals and environmental conditions.
Results and discussion
- Additional information on results:
- Sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results: negative
The publication reported that sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila. No information is provided on experimental materials and methods. - Executive summary:
The publication reported that sodium iodate showed no mutagenic activity by the recessive lethal test using Drosophila. No information is provided on experimental materials and methods.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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