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Ecotoxicological information

Toxicity to microorganisms

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Link to relevant study record(s)

Reference
Endpoint:
activated sludge respiration inhibition testing
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is found to be readily biodegradable and the applied test concentrations are in the range of concentrations that can be expected in the influent of a sewage treatment plant
Reason / purpose:
data waiving: supporting information
Related information:
Composition 1

Description of key information

NOEC (3 h) = 5 mg/L

Key value for chemical safety assessment

EC10, LC10 or NOEC for microorganisms:
5 mg/L

Additional information

According to the ECHA Guidance document R7b, no further test on the toxicity to microorganisms has to be conducted if the toxicity control in a ready biodegradability test shows no inhibitory effects on microorganisms or when the substance is readily biodegradable. No toxicity control was included in the biodegradability test according to OECD 301 D and in compliance with GLP (study no. RE910127). However, the substance was observed to be readily biodegradable and further no inhibition of the microbial activity at a substance concentration of 2 mg/L and 5 mg/L was observed. A test to evaluate the respiration inhibition of activated sludge is not necessary and was, therefore, waived