Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-907-1
CAS number: 111-78-4
no further results
Three groups of 6 male rats each were exposed nose-only for a single, 4
hour period to vapors of the test item in air at chamber vapor
concentrations of 1400, 2700 or 4300 ppm. Mortality was 0/6, 1/6 and 4/6
at 1400, 2700 and 4300 ppm respectively. By 3 hours into the exposure
all rats failed to respond to external sound stimuli. At the end of
exposure, the 2 rats at 4300 ppm and 4 rats at 2700 ppm were immobile.
Threee rats at 1400 ppm exhibited ataxia. Other clinical signs of
toxicity observed after exposure: ocular discharge,
lethargy, irregular respiration. Ocular discharge,
ruffled fur or stained perineum were observed up
to 4 days following exposure.
On an acute inhaltion basis, test item is considered slightly toxic.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again