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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 25, 2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
other: BS4633: Method for the Determination of Crystallizing Point
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
Swiss GLP compliance programme (inspected on September 09 and 30, 2002/ signed on December 2002)
Type of method:
method to determine freezing temperature
Specific details on test material used for the study:
- Physical state: Colourless liquid
- Storage condition of test material: Refrigerator (between 0 and 10 °C under nitrogen)
Key result
Melting / freezing pt.:
-12 °C
Decomposition:
no
Remarks on result:
other: 261 ± 0.5 K

Table 4.2/1: Determinations 1 and 2

Determination 1

Time (s)

Temperature (K)

Determination 2

Time (s)

Temperature (K)

0

297

0

294

30

293

30

288

60

285

60

284

90

283

90

282

120

278

120

275

150

274

150

274

180

271

180

271

210

268

210

267

240

264

240

265

270

262

270

263

300

261

300

262

330

259

330

261

360

261

360

261

390

261

390

261

420

261

420

261

450

261

450

261

480

261

480

261

Conclusions:
The freezing temperature of test substance has been determined to be -12 ± 0.5 °C (261 ± 0.5 K).
Executive summary:

The freezing point of the test substance was determined according to OECD 102/EU A1 guideline, using BS4633 method for the determination of crystallizing point. The determination was carried out in duplicate and the mean final temperature was retained.

The freezing temperature of test substance has been determined to be -12 ± 0.5 °C (261 ± 0.5 K).

Description of key information

Freezing (i.e. liquid-solid transition) occurs at the temperature of -12 ± 0.5 °C (261 ± 0.5 K).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
-12 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC/BS method and under GLP, is available. It is considered as a key study. The result is retained as key data.