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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 611, 1961
Year:
1961
Bibliographic source:
ChemIDplus Lite
Reference Type:
publication
Title:
Pharmacology: International Journal of Experimental and Clinical Pharmacology. Vol. 15, Pg. 485, 1977.
Year:
1977
Bibliographic source:
ChemIDplus Lite data base

Materials and methods

Principles of method if other than guideline:
Method not available
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
(1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-
EC Number:
606-172-9
Cas Number:
1893-33-0
Molecular formula:
C21H30FN3O2
IUPAC Name:
(1,4'-Bipiperidine)-4'-carboxamide, 1'-(3-(p-fluorobenzoyl)propyl)-

Test animals

Species:
other: rat and mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levelsopen allclose all
Sex:
not specified
Dose descriptor:
LD50
Effect level:
160 mg/kg bw
Based on:
not specified
Remarks on result:
other: on rat
Sex:
not specified
Dose descriptor:
LD50
Effect level:
490 mg/kg bw
Based on:
test mat.
Remarks on result:
other: on mouse

Applicant's summary and conclusion

Interpretation of results:
other: Toxic if swllowed
Conclusions:
Following CLP criteria the substance is classified into category 4, Toxic if swallowed.