Registration Dossier

Administrative data

First-aid measures

Description of the first aid measures - Don’t induce vomiting by untrained person.In case of inhalation - Supply fresh air. In case of irritation of the respiratory tract or continuing discomfort consult a physician.In case of skin contact - Wash with soap and plenty of water; compensate the loss of skin fat by using suitable hand lotion. In case of continuing skin irritation consult a physician.In case of eye contact - Rinse opened eye for 10 minutes with running water, in case of continuing discomfort consult immediately an eye specialist.In case of ingestion - Rinse mouth thoroughly and drink plenty of water (2 glasses). In case of acute poisoning or indisposition consult immediately a physician. When indicated take advice by emergency telephone.Indication of any immediate medical attention and special treatment needed - In case of poisoning call immediately an emergency physician.

Fire-fighting measures

Extinguishing mediaSuitable extinguishing media - water, foam, C02, powderExtinguishing media which must not be used for safety reasons - Not applicableSpecial hazards arising from the substance or mixture - In case of fire hazardous gases may be produced (Carbon oxides, NOx).Advice for firefighters - Self-contained breathing apparatus. Avoid escape of fire water into surface water, groundwater and soil.

Accidental release measures

Personal precautions, protective equipment and emergency procedures - Avoid skin and eye contact, use suitable personal protective equipment, avoid dust clouds.Environmental precautions - Avoid soil and groundwater contamination.Methods and material for containment and cleaning up - Take up spilled product with a vacuum cleaner or mop up wet. Avoid generation of dust clouds, final cleaning of affected area using water (if necessary diluted sulphuric acid, 3-4%). Vacuum cleaner has to satisfy specification for combustible dusts (Class BI or volume limited to 50 litre and power consumption < 1200 W).

Handling and storage

Precautions for save handling - Avoid contact with the product, use suitable personal protective equipment, avoid generation of dust clouds, keep clean workplace, remove contaminations with product immediately.Precautions against fire and explosion - In case of dust forming production steps (such as filling, mixing) explosive dust/air mixtures might be generated. Exclude ignition sources / take measures against electrostatic charging. Risk assessment for hazards for explosive dust/air mixtures has to be performed for all production steps and appropriate protective measures have to be implemented by responsible person.Conditions for save storage, including any incompatibilitiesTechnical measures and storage conditions - Keep containers tightly closed in a dry place. Store in the original package to protect from light. This product (API) does not require any special temperature storage conditions. Store separate from food.Requirements for storage rooms and vessels - Protect containers from weather and humidity.Storage class VCI: Class 11 (Combustible solid matter)

Transport information

Land transport (ADR/RID)

UN number:
No subject to transport regulation
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Class:
No subject to transport regulation
Classification code:
No subject to transport regulation
Packaging group:
No subject to transport regulation
Labels:
No subject to transport regulation
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Inland waterway transport (ADN(R))

UN number:
No subject to transport regulation
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Class:
No subject to transport regulation
Classification code:
No subject to transport regulation
Packaging group:
No subject to transport regulation
Labels:
No subject to transport regulation
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Marine transport (IMDG)

UN number:
No subject to transport regulation
Proper shipping name and description:
No subject to transport regulation
Chemical name:
No subject to transport regulation
Class:
No subject to transport regulation
Packaging group:
No subject to transport regulation
EmS code:
No subject to transport regulation
Labels:
No subject to transport regulation
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Air transport ICAO/IATA

UN number:
No subject to transport regulation
Proper shipping name and description:
No subject to transport regulation
Chemical name:
No subject to transport regulation
Class:
No subject to transport regulation
Packaging group:
No subject to transport regulation
Labels:
No subject to transport regulation
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Exposure controls / personal protection

Control parametersOccupational exposure limits (AGW) Germany - Not definedOccupational exposure limits of EU - Not definedAdditional information - In studies concerning the health assessment of the use of quinine in foods the FAO/WHO Expert Committee on Food Additives (JECFA) determined a NOEL (No Observed Effective Level) at 0.9 mg/kg bw/day of quinine, equivalent to an intake of 72 mg quinine free base/person/day.Exposure controls - Avoid dust formation by technical measures (closed equipment, local extraction). If the formation of dust can not be excluded, avoid the contact with the substance by appropriate personal protective equipment (protective clothing, inhalation protection, safety glasses). Follow the protective measures according TRGS 540 "Sensibilisierende Stoffe”. (TRGS — Technical regulation for dangerous chemicals)Personal protection equipment - Respiratory protection - Dust mask filter type FFP2Hand protection - The glove material must be impermeable and resistant against the product. Test the leak tightness before use. In case of longer wearing take measure against skin exposure by humidity (undergloves and skin care). Test results for different glove materials are not available at present. From experience glove materials as nitrile rubber, butyl rubber, chloroprene rubber, fluorine rubber are appropriate for protection against not dissolved solids.Eye protection - Safety goggles with side frame, in case of dust formation use cover-typed safety goggles.Body protection - Body covering protective clothingMeasures for skin care - Apply appropriate skin protection lotion before and after work.Environmental Exposure Controls - No additional measures necessary.

Stability and reactivity

Reactivity - Less reactive substance.Chemical stability - Stable under recommended storage conditions for a minimum of 5 years.Possibility of hazardous reaction - Normally no hazardous reactions are expected.Conditions to avoid - At higher temperature and acid conditions the degradation product Quinicine is formed.Incompatible materials - Strong oxidizing agents lead to decomposition of the product.Hazardous decomposition products - Hazardous decomposition products are not produced as a result of use, storage, spill and heating.

Disposal considerations

Appropriate disposal / Product - Wastes must be disposed of in compliance with the respective national regulations.Recommendation - Request the applicable waste code from the waste disposal contractor.Waste codes / waste designations according to EWC / AVV - Classify waste to the group 0701 (wastes from the manufacture, formulation, supply and use of basic organic chemicals). Identify the waste group for hazardous or non-hazardous waste according §3, section 2 AVV. Furthermore use wastecode 16 03 05 (organic wastes, containing dangerous substances) for off- specification batches or unusable product.Waste treatment methods - Hazardous waste has to be delivered to an incineration plant. Quinine containing solutions should be not disposed through waste water.Contaminated packaging - Contaminated packaging or containers have to be disposed as hazardous wastes. Waste code: 15 01 10 (packaging, containing residues of or contaminated by dangerous substances)Purified packaging - Purified packaging can be recycled.