Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is no information available on skin sensitisation in humans or respiratory sensitisation in humans or animals. In animal skin sensitisation studies, negative results were obtained in both a maximisation and a Buehler study, although both had limitations in either conduct or reporting. However, in view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.


Migrated from Short description of key information:
In animal skin sensitisation studies, negative results were obtained in both a maximisation and a Buehler study.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

There is no information available on respiratory sensitisation in humans or animals. However, in view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.


Migrated from Short description of key information:
In view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces respiratory sensitisation suggests that these endpoints are not of concern for human health and no further information is required.

Justification for classification or non-classification

In view of the use of naphthalene for many years in occupational and consumer settings, the absence of reports that naphthalene produces skin or respiratory sensitisation suggests that these endpoints are not of concern for human health and no classification is required.