Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1986
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
1-CHLORO-2-PROPANONE
Author:
National Institute of Health
Year:
2009
Bibliographic source:
National Library of Medicine, http://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+78-95-5

Materials and methods

GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Chloroacetone
EC Number:
201-161-1
EC Name:
Chloroacetone
Cas Number:
78-95-5
Molecular formula:
C3H5ClO
IUPAC Name:
1-chloropropan-2-one

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Remarks:
Migrated information
Conclusions:
Based on the literature data monochloroacetone has to be concidered as toxic with an LD50 of about 100mg/kg bw.