Registration Dossier
Registration Dossier
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EC number: 203-742-5 | CAS number: 110-16-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 969
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- GLP compliance:
- no
- Test type:
- other: no data
Test material
- Reference substance name:
- Maleic anhydride
- EC Number:
- 203-571-6
- EC Name:
- Maleic anhydride
- Cas Number:
- 108-31-6
- Molecular formula:
- C4H2O3
- IUPAC Name:
- furan-2,5-dione
- Details on test material:
- See also SIDS Initial Assessment.
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Duration of exposure:
- 1 h
- Concentrations:
- 0.72 mg/L
- No. of animals per sex per dose:
- 6 rats in total
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- > 0.72 mg/L air
- Mortality:
- No mortality occurred.
- Clinical signs:
- other: Generalized inactivity, hyperpnea, sedation within 15 minutes of exposure
- Gross pathology:
- No significant findings
Applicant's summary and conclusion
- Conclusions:
- The LC50 was >0.72 mg/L air for rats exposed to the maleic acid for 1 hour.
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