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EC number: 203-742-5
CAS number: 110-16-7
The result of the local lymph node assay of Weber (2004) the stimulation
index of 11.2 after exposure to 1% indicates that Maleic acid is a skin
sensitizer. Dermal contact therefore has to be excluded completely.
Beyond this, dermal contact may facilitate or even induce the
development of a respiratory sensitization.
A quantitative dermal DNEL has not been derived, since such a value does
not aid in a relevant risk assessment for dermal exposure. A qualitative
assessment has been performed, using the experience of control measures
in practice and no cases of sensitization among the employees. No
difference will be made between short term and long term exposure as
sensitization may also develop after several short term exposures as well
The submitted substance is intended for use by the industry.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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