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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

NOEC (Daphnia magna, 21 d) = 10 mg/L (reproduction rate)
EC50 (Daphnia magna, 21 d) = 77 mg/L (reproduction rate)

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
10 mg/L

Additional information

A study investigating the long-term toxicity of maleic anhydride to Daphnia magna is published. The study was a performed as a prolonged toxicity test according to a proposal of the German Federal Environmental Agency (1984). The reproduction of Daphnia magna was determined within 21 days of exposure to the substance. A NOEC of 10 mg/L and an EC50 of 77 mg/L were determined (Hüls AG, 1988).