Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 203-742-5 | CAS number: 110-16-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Handbook data are considered to be from a trusted source
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Ullmanns Encyklopädie der technischen Chemie, 4th edition., Vol. 16, p. 413
- Author:
- E. Bartholome, E. Biekert, H. Hellmann, H. Ley, W.M. Weigert, E. Weise
- Year:
- 1 978
- Bibliographic source:
- Weinheim, New York, Verlag Chemie
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Maleic acid
- EC Number:
- 203-742-5
- EC Name:
- Maleic acid
- Cas Number:
- 110-16-7
- Molecular formula:
- C4H4O4
- IUPAC Name:
- but-2-enedioic acid
Constituent 1
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 708 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Criteria used for interpretation of results: OECD GHS
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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