Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

Currently viewing:

Administrative data

First-aid measures

Description of first aid measures
General information: Move victim to fresh air, put at rest and loosen restrictive clothing. Do not allow victim to become chilled. Keep victim warm. If victim is at risk of losing consciousness, position and transport on their side. Call a physician immediately.

After inhalation: Move victim to fresh air, put at rest and loosen restrictive clothing. If breathing becomes irregular or ceases, apply mouth-to-mouth resuscitation or artificial respiration immediately, where required supply oxygen. Immediately get medical attention.

In case of skin contact: Immediately remove any wetted clothing, shoes or stockings. After contact with skin, wash immediately with soap and plenty of water. Then cream your skin. In case of skin irritation, consult a physician.

After eye contact: Immediately flush eyes with plenty of flowing water for 10 to 15 minutes holding eyelids apart. Subsequently seek the immediate attention of an ophthalmologist.

After swallowing: If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label. Give activated carbon, in order to reduce the resorption in the gastro-enteric tract.

Most important symptoms and effects, both acute and delayed
Burning eyes and skin. fatigue, nausea, unconsciousness.

After inhalation: For the development of any overt signs of toxicity in humans, accidental exposures to extremely large amounts of acetone by inhalation of vapour or ingestion of liquid are necessary (e. g. several thousand ppm of acetone vapour).

In case of ingestion: Gastric and intestinal problems.

After contact with skin: Irritant. Repeated exposure may cause skin dryness or cracking, due to defatting properties. No indication for sensitising properties in humans.

After eye contact: Irritant.

Indication of any immediate medical attention and special treatment needed
Combat acidosis. Monitor alkali reserves. Monitor breathing. If breathing becomes irregular or ceases, apply mouth-to-mouth resuscitation or artificial respiration immediately, where required supply oxygen.

Attention: several hours latency period. In severe cases, pneumonia or a pulmonary edema may develop.

Fire-fighting measures

Extinguishing media
Suitable extinguishing media: Extinguishing powder, alcohol resistant foam, carbon dioxide, water fog.

Extinguishing media which must not be used for safety reasons: Full water jet

Special hazards arising from the substance or mixture
Highly flammable. Explosive mixtures with air may even form at room temperature. Beware of reignition. In case of fire may be liberated: Carbon monoxide and carbon dioxide.

Advice for firefighters
Special protective equipment for firefighters: Wear a self-contained breathing apparatus and chemical protective clothing.

Additional information: Hazchem-Code: •2YE
Do not expose to high temperature. Danger of bursting and explosion. Use fine water spray to cool endangered containers. Move undamaged containers from immediate hazard area if it can be done safely. Do not allow fire water to penetrate into surface or ground water. Fire residuals and contaminated extinguishing water must be disposed of in accordance with the regulations of the local authorities.

Fire class: B
Mixtures with 4% acetone mixed with 96% water still have a flash point of 54 °C.

Accidental release measures

Personal precautions, protective equipment and emergency procedures
Remove persons not involved upwind. Wear a self-contained breathing apparatus and chemical protective clothing. Solvent-resistant protective clothing recommended.

Environmental precautions
Plug leak if safely possible. Do not allow to enter drains, surface waters, basements or pits. When released into the environment, alert police and fire brigade. Seal all low level rooms. Danger of explosion!

Methods and material for containment and cleaning up
In case of spills of large quantities: Dam spills and pump to remove. Explosion protection required. Absorb leftover product with non-flammable liquid-binding material (e.g. earth, sand, vermiculite or ground sand stone) and place in closed containers for disposal. Flowing water: Dilution occurs quickly. In case of large spills/leaks inform appropriate local, state, and federal spill reporting authorities. Standing water: Seal off. Remove all sources of ignition.

Additional information: Remove all sources of ignition. Vapours spread at floor level. Cover drainage holes and evacuate basement. Dilute with plenty of water. Use only explosion-protected equipment/instruments.

Liquid: Very highly flammable. Liquid evaporates very quickly.
Vapours: Very highly flammable.
Vapours form potentially explosive mixtures with air. Heavier than air, they proceed at floor level and may backflash over great distances when ignited. Ignition by hot surfaces, sparks and open flames.

Solubility in water: complete
Mixtures with 4% acetone mixed with 96% water still have a flash point of 54 °C in case of important spills, risk of ignition of the acetone-water mixture. Potentially explosive mixtures with air may form above water surface.

Handling and storage

Precautions for safe handling
Advices on safe handling: Provide adequate ventilation, and local exhaust as needed. Provide room air exhaust at ground level. Concentrated vapours are heavier than air. Avoid the formation of aerosol. Do not breathe vapours. Use only explosion-protected equipment/instruments. Do not use air pressure.

Precautions against fire and explosion: Exposure to temperatures exceeding 50 °C will increase pressure: resulting in danger of bursting or explosion. Keep away from sources of ignition. - No smoking. Take precautionary measures against static discharge. Beware of reignition. Potentially explosive mixture may form within partially empty containers. Emergency cooling must be provided for in case of a fire in the vicinity. Do not weld.

Conditions for safe storage, including any incompatibilities
Requirements for storerooms and containers: Keep container dry. Keep container tightly closed in a cool, well-ventilated place. Protect from direct sunlight.
Steel, stainless steel, and aluminium are stable container materials. Copper may be attacked.
Unsuitable container/equipment material: May attack plastics.

Hints on joint storage: Do not store together with combustible or self-igniting materials or any highly flammable solids. Peroxide may form when product is exposed to light and air.

Further details: Potentially explosive mixture may form within partially empty containers.
For outdoor storage: Use only equipment approved for use in 1 zone.
For indoor storage: Use only equipment approved for use in 2 zone.
Storage class: 3 Flammable liquids

Specific end use(s)
solvent

Transport information

Land transport (ADR/RID)

UN number:
UN 1090
Proper shipping name and description:
UN 1090, ACETONE
Chemical name:
Acetone
Language:
English
Class:
Class 3, Code: F1
Classification code:
Danger code (Kemmler): 33
Packaging group:
II
Labels:
3
Remarks:
Hazard label: 3
Limited quantities: 1 L
EQ: E2
Contaminated packaging - Instructions: P001 IBC02 R001
Special provisions for packing together: MP19
Portable tanks - Instructions: T4
Portable tanks - Special provisions: TP1
Tank coding: LGBF
Tunnel restriction code: D/E

Inland waterway transport (ADN(R))

UN number:
UN 1090
Proper shipping name and description:
UN 1090, ACETONE
Chemical name:
Acetone
Language:
English
Class:
3
Packaging group:
II
Remarksopen allclose all

Marine transport (IMDG)

UN number:
UN 1090
Proper shipping name and description:
UN 1090, ACETONE
Chemical name:
Acetone
Class:
Class 3, Subrisk -
Packaging group:
II
EmS code:
F-E, S-D
Labels:
3
Remarks
Special provisions: -
Limited quantities: 1 L
EQ: E2
Contaminated packaging - Instructions: P001
Contaminated packaging - Provisions: -
IBC - Instructions: IBC02
IBC - Provisions: -
Tank instructions - IMO: -
Tank instructions - UN: T4
Tank instructions - Provisions: TP1
Stowage and segregation: Category E.
Properties and observations: Colourless, clear liquid, with a characteristic mint-like odour. Flashpoint: -20°C to -18°C c.c. Explosive limits: 2.5% to 13%. Miscible with water.

Air transport ICAO/IATA

UN number:
UN 1090
Proper shipping name and description:
UN 1090, ACETONE
Chemical name:
Acetone
Class:
Class 3
Packaging group:
II
Labels:
3
Remarks
Hazard: Flamm. liquid
EQ: E2
Passenger Ltd.Qty.: Pack.Instr. Y341 - Max. Net Qty/Pkg. 1 L
Passenger: Pack.Instr. 353 - Max. Net Qty/Pkg. 5 L
Cargo: Pack.Instr. 364 - Max. Net Qty/Pkg. 60 L
ERG: 3H
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Control parameters
Occupational exposure limit values:
Type Limit value
Europe: IOELV: TWA 1.210 mg/m³; 500 ppm
Great Britain: WEL-STEL 3.620 mg/m³; 1.500 ppm
Great Britain: WEL-TWA 1.210 mg/m³; 500 ppm
Ireland: 8 hours 1.210 mg/m³; 500 ppm IOELV

DNEL/DMEL:
DNEL Long-term, workers, dermal: 186 mg/kg bw/d.
DNEL Short-term, workers, inhalative: 2420 mg/m³
DNEL Long-term, workers, inhalative: 1210 mg/m³
DNEL Long-term, consumers, oral: 62 mg/kg bw/d.
DNEL Long-term, consumers, dermal: 62 mg/kg bw/d.
DNEL Long-term, consumers, inhalative: 200 mg/m³

PNEC: PNEC water (freshwater): 10.6 mg/L.
PNEC water (marine water): 1.06 mg/L.
PNEC water (intermittent release): 21 mg/L.
PNEC sediment (freshwater): 30.4 mg/kg dwt.
PNEC sediment (marine water): 3.04 mg/kg dwt.
PNEC soil: 33.3 mg/kg dwt.
PNEC sewage treatment plant: 100 mg/L.

Exposure controls
Explosion protection required. Provide good ventilation and/or an exhaust system in the work area.

Occupational exposure controls
All information for relevant exposure scenarios including operational conditions and risk management measures are listed in 'Annex II: worker exposure and risk assessment'.

Respiratory protection: For short exposures or in case of accident: Filter apparatus, type AX (EN 371). Have a breathing apparatus that is not dependent on the circulating air ready for emergencies.

Hand protection: Protective gloves according to EN 374.
Glove material: Butyl caoutchouc (butyl rubber) - Layer thickness >= 0,5 mm.
Breakthrough time: >480 min.
Observe glove manufacturer's instructions concerning penetrability and breakthrough time.

Eye protection: Tightly sealed safety glasses according to EN 166.

Body protection: Use solvent-resistant protective clothing.
Recommendation: Flame-retardant protective clothing, antistatic. safety shoes according to EN 345-347.

General protection and hygiene measures:
Wash hands before breaks and after work. Avoid contact with skin and eyes. When using do not eat, drink or smoke. Have eye wash bottle or eye rinse ready at work place.
Alternatives to the following personal protective measures can only be determined in agreement with a responsible safety experts.

Consumer exposure controls
All information for relevant exposure scenarios including operational conditions and risk management measures are listed in 'Annex II: consumer exposure and risk assessment'.

Environmental exposure controls
All information for relevant exposure scenarios including operational conditions and risk management measures are listed in 'Annex III: Environmental Exposure and Risk Assessment and Annex IV: Environmental Exposure Calculation Tool'.

Stability and reactivity

Reactivity
Acetone reacts in presence of bases. Vapours form potentially explosive mixtures with air. Heavier than air, they proceed at floor level and may backflash over great distances when ignited. May become electrostatically charged.

Chemical stability
Product is stable under normal storage conditions.

Possibility of hazardous reactions
No hazardous reactions known.

Conditions to avoid
Highly flammable. Concentrated vapours are heavier than air. Forms explosive mixtures with air, also in empty, uncleaned containers. May produce, when being mixed with chloridized hydrocarbons and exposed to light, strongly irritating chloric acetone.

Incompatible materials
Attacks many plastics and rubbers. On contact with barium hydroxide, sodium hydroxide and many other alkaline materials condensation may occur.
Avoid contact with strong oxidizing agents, alkalis and amines.

Hazardous decomposition products
In case of fire may be liberated: Carbon monoxide and carbon dioxide.

Disposal considerations

Waste treatment methods
Product
Waste key number: 07 01 04* = Wastes from the manufacture, formulation, supply and use (MFSU) of basic organic chemicals: organic solvents, halogen-free
* = Evidence for disposal must be provided.

Recommendation: Incinerate as hazardous waste according to applicable local, state, and federal regulations. Do not dispose of with household waste.

Contaminated packaging
Recommendation: Dispose of waste according to applicable legislation. Handle contaminated packages in the same way as the substance itself. Non-contaminated packages may be recycled.