Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-235-6
CAS number: 1314-41-6
The acute oral toxicity of "LITHARGE lead oxide was investigated
according to ATC method in one step using 3 male and 3 female rats.
Three female animals were given a single oral administration of the test
article Litharge lead oxide at a dose of 2000 mg/kg. Clinical
observations were carried out at regular intervals during the 14-day
observation period. Body weights were determined immediately before
treatment and on 7 days and 14 p.a. Gross pathological examinations were
carried out immediately at termination on all animals.
The following results were obtained:
-No animals died during the course of the 14-day observation period
following the dose of 2000 mg/kg.
-No abnormal clinical signs were observed
-There was no influence of the treatment on the body weight development
in all male and female animals during the 14-day observation period.
-Gross pathological examinations on day 14 p.a. did not reveal test
According to the EEC Directive 2001/59, 6 August 2001 and the
Gefahrstoffverordnung (GefStoffV) of 15 November 1999 (BGB1. I, p.2233),
the test article LITHARGE lead oxide can be classified as "non-toxic",
since the oral LD50 value after 24 h and 14 days is expected to be
higher than 2000 mg/kg in male and female Wistar rats.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Damit Sie die Website optimal nutzen können, verwenden wir Cookies.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again