Registration Dossier
Registration Dossier
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EC number: 238-694-4 | CAS number: 14644-61-2
Carcinogenicity
Administrative data
Description of key information
The available information was not considered sufficient for covering the endpoint. However, this Annex X endpoint is not mandatory. Moreover, supporting information indicates no carcinogenic effect at drinking water dose levels of 5 ppm Zr in life-time studies with rats and mice.
Key value for chemical safety assessment
Justification for classification or non-classification
Additional information
Three supporting studies were identified (Schroeder et al., 1968; Kanisawa and Schroeder, 1969; Schroeder et al., 1970). These studies were not considered reliable but give however an indication that zirconium, administered to rats or mice as zirconium sulfate via drinking water (single dose of 5 ppm Zr) is not carcinogenic.
The information was not considered sufficient to cover this endpoint, however, since carcinogenicity is an Annex X endpoint it is not mandatory for the current dossier.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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