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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Salmo gairdneri: NOEC(50d): 0.6 mg/L, LC50 (50d): 1.15 mg/L (based on mortality, Calamari et al., 1979) 
Salmo gairdneri: NOEC(30d): 20 mg/L (based on growth; Calamari et al., 1979)
Oncorhynchus mykiss: NOEC(30d) >= 10 mg/L (based on mortality and histopathological changes, Calamari, Galassi and Da Gasso, 1979)

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.6 mg/L

Additional information

In 1979, Calamari et al. performed an early life stage egg-fry-test with Salmo gairdneri (new name: Ocorhynchus mykiss). The time duration was 50 days. A NOEC of 0.6 mg/L as well as a LC50of 1.15 mg/L are reported as results. The basis for effect was mortality in this study.

Juvenile Salmo gairdneri (new name: Oncorhynchus mykiss) were exposed to different concentrations of dimethylamine for 30 days (Calamari et al., 1979). A NOEC of 20 mg/L is reported as result. During the experiment no mortality and no effect on the body weight were observed. Additionally, no histopathological changes were observed after the study period.

Young rainbow trouts (Oncorhynchus mykiss) used to investigate the mortality and histopathological changes after a 30 day exposure towards dimethylamine (Calamari, Galassi and Da Gasso, 1979). The test was conducted at 15 °C at pH 7.4 with a water hardness of 320 mg/L as CaCO3. Based on both investigated endpoints, the NOEC was determined to be equal or greater than 10 mg/L.