Registration Dossier

Administrative data

Description of key information

Sodium acrylate is not irritating to the skin and eyes.

Key value for chemical safety assessment

Additional information

Skin irritation:


Sodium acrylate (no data on purity) was tested using an internal method (BASF test) by applying aqueous test substance solutions for 1, 5 or 15 minutes (50 %) as well as for 20 hours (30 and 50 %, respectively) to the rabbit skin under occlusive conditions. Irritation scores were read 24, 48, and 72 hours and 8 days after application. Mean scores (24-48-72 hrs) after occlusive exposure for 20 hrs were for erythema 0.50, 0.67, 0, and 0, and for edema 0, 0, 0, and 0. All skin reactions were fully reversible within the study period of 8 days (BASF AG, 1961).


Based on the presented test results, sodium acrylate has no skin irritating properties.



Eye irritation:


In an eye irritation study in White Vienna rabbits conducted according to an internal study protocol, 50 mg of the undiluted substance (no data on purity) were instilled into the eye of 2 rabbits. The adjacent eyes of the same animals were treated with talcum powder and served as control. The eyes were not washed out as recommended by OECD TG 405. Eye reactions were read after 1,  24, 48 and 72  hours. No eye reactions indicative of irritation were observed at any reading. Thus, the study was discontinued after 48 hrs (BASF AG 1961).


Under the conditions of the study, sodium acrylate was not irritating to the eyes of rabbits.



Respiratory irritation:


There are no experimental indications for a potential of sodium acrylate to cause respiratory irritation. Due to the substance’s low vapour pressure, and since the solid test substance was not irritating to the mucosa in an eye irritation study, irritation of the respiratory tract upon inhalation of vapours or dust particles is not to be expected.

There are no human data available concerning the potential for respiratory irritation of sodium acrylate.

Justification for classification or non-classification

EU classification according to Annex VI of Directive 67/548/EEC: no classification required

GHS classification (GHS UN rev.3, 2009): no classification required