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Short-term toxicity to fish

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Description of key information

Acute harmful to fish.

Key value for chemical safety assessment

Additional information

No data on acute toxicity in fish are available for sodium acrylate. Therefore, results from investigations on the structural analogous substance acrylic acid were used for the assessment of sodium acrylate.

Acrylic acid was tested in an acute toxicity test with Salmo gairdneri under flow-through conditions. Biological and chemical procedures followed the U.S. EPA-TSCA, 40 CFR, Part 797 Guideline 797.1400. Based on mean measured concentrations, the 96-hour LC50 was determined to be 27 mg/L. Reported behavioural effects were: loss of equilibrium, on bottom orientation, quiescence and erratic swimming.

As supporting study, an acute fish test according to the 92/69/EEC part C1 with Danio rerio using a semi-static test design is available. Analytical concentration control by spectrophotometrical measurements revealed a recovery rate of >80 %. Therefore, effect values were based on nominal concentrations. The 96-hour LC50 was determined to be approx. 222 mg/L.

In a saltwater study conducted using the sheepshead minnow (BAMM, 1995), the 96-hour LC50 was estimated to be 236 mg/L. This study was conducted according to OECD Guideline 203 using a flow-through test design. The LC50 value was based on analytically determined concentrations. Analytical recovery was between 90 and 110 % of nominal concentrations. Mortality occurred only in the highest concentration of 297 mg/L. Clinical signs and symptoms observed were: lying on bottom, lethargy, surfacing, loss of equilibrium. The NOEC was determined to be 187 mg/L. Even though being a OECD-TG-study conducted in compliance with GLP regulations, this study is only valid with restrictions since during a seven-hour-period a malfunction in the diluter occurred that caused test substance concentrations to rise up to 200 % of nominal.

In conclusion, based on the results of the most sensitive species testing acrylic acid, sodium acrylate is acute harmful to fish.