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Sediment toxicity

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Description of key information

GLP/guideline compliant 28-d study in L. varigaetus (2% TOC)
GLP/guideline compliant 28-d study in L. varigaetus (5.0% TOC)
GLP/guideline compliant 28-d study in C. riparius
GLP compliant 14-d study in C. tentans
GLP compliant/28-d study in Hyalella azteca

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater sediment:
90 mg/kg sediment dw

Additional information

The toxicity of TBBPA to sediment dwelling organisms was tested in 5 studies:

1) Breteler (1989): 14 d study in Chironmus tetans at nominal concentrations 13, 25, 50, 100, and 200 mg/kg TBBPA.

2)Krueger et al. (2005): 28 day study in Chironomous riparius at nominal concentrations 63, 125, 250, 500, and 1000 mg a.i./kg.

3) Krueger et al. (2002): 28 day study in Lumbriculus variegates in 2% total organic carbon (TOC) sediment at nominal concentrations of 90, 151, 254, 426, 715, 1200 mg/kg.

4) Krueger et al. (2001): 28 day study in L. varegates in 5% TOC sediment at nominal concentrations of 90, 151, 254, 426, 715, 1200 mg/kg.

5) Krueger et al. (2006): 28 day study in Hyalella azeteca at nominal concentrations of 63, 125, 250, 500, 1000 mg/kg TBBPA.

The four 28 day studies were conducted under GLP conditions and according to international guidelines with analytical confirmation of sediment concentrations.

The 28 day NOEC, expressed as mg TBBPA/kg sediment dry weight, ranged from 90 - 254. The lowest NOEC was observed in L. varigatus in the sediments that contained a TOC content of 2%, while the highest was in the same species tested in sediments with a 5% TOC content.