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EC number: 203-312-7
CAS number: 105-59-9
From the water surface, the 2,2 -Methyliminodiethanol (CAS 105 -59 -9) will not evaporate into the atmosphere.
Article 13 of Regulation (EC) No 1907/2006, it is laid down that
information on intrinsic properties of substances may be generated by
means other than tests, provided that the conditions set out in Annex
XI (of the same Regulation) are met. Furthermore, according to Article
25 of the same Regulation testing on vertebrate animals shall be
undertaken only as a last resort.
to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used
if (1) the scientific validity of the (Q)SAR model has been
established, (2) the substance falls within the applicability domain
of the (Q)SAR model, (3) the results are adequate for the purpose of
classification and labeling and/or risk assessment and (4) adequate
and reliable documentation of the applied method is provided.
the assessment of the2,2'-methyliminodiethanol(CAS
105-59-9) (Q)SAR results were used for the estimation of the Henry’s
Law constant. The criteria listed in Annex XI of Regulation (EC) No
1907/2006 are considered to be adequately fulfilled and therefore the
endpoint(s) sufficiently covered and suitable for risk assessment.
further experimental studies on the Henry’s Law Constant are not
bond estimation method gives a value of 8.72E-06 Pa*m³/mol (HENRYWIN
Program, v3.20; EPI Suite v4.10; BASF SE, 2013), which is
representative for the uncharged molecule. The substance is within
the applicability domain of the model. At environmental conditions
the molecule is expected to be ionised;
the estimate may overestimate the evaporation potential of the
substance. It can be concluded that the
substance will not evaporate from the water surface into the
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