Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-201-8
CAS number: 79-38-9
In accordance with section 1 of REACH (Regulation (EC) No 1907/2006) Annex XI the bioaccumulation study required in section 9.3.2 Annex IX of REACH (Regulation (EC) No 1907/2006) is not proposed by the registrant as CTFE is a gas at ambient condition with a moderate water solubility and an high tendency to rapidly volatilise from water to the air.On the basis of the properties of CTFE it is expected that the substance primarily and rapidly partitions to the atmosphere.The EQC Fugacity III Model confirms that the whole amount of CTFE released to air remains in this compartment. The model was run assuming emission only to air. In case of an accidental emission, CTFE is only released to air, because CTFE is a volatile gas at ambient conditions with a boiling point ranging from -26.2°C to -26.8°C.
Chlorotrifluoroethylene (CTFE) is a volatile gas at ambient conditions
with a boiling point in the range of -26.2°C (The Beilstein database.
Reference: Miller - 1951 ) to -26.8°C (The Beilstein database.
Reference: Henne - 1948) a vapour pressure of 612 kPa at 25°C (ISCS No.
0685, NIOSH) . CTFE is also characterized by a moderate water solubility
of 380 mg/L.
The value of water solubility of 380 mg/l was
experimentally determined in a completely sealed system with an
atmosphere saturated with CTFE. Althoughthe
value of 380 mg/l itself reveals a moderate water solubility, it
represents an overestimation of the actual water solubility of CTFE in
the natural system since the experimental conditions did not represent
the natural conditions.
The Henry’s Law constant
of CTFE was calculated to be 31.500 Pa m3/mol (HENRYWIN v3.20, EPI Suite
v4.0), suggesting that the substance is expected to rapidly volatilise
from water to the air in fact
the Guidance on Information
Requirements and Chemical Safety Assessment Chapter R.7a: Endpoint
Specific Guidance, Appendix R.7.1-4 indicates that substances with a
Henry's Law constant of around 1 hPa m3/mole will rapidly volatilise
Hence, due to the gaseous nature of the substance and its partition to
the atmosphere, as well as the consequent difficulty to appropriately
test CTFE and provide meaningful results, no experimental
bioaccumulation data are reported. However, in order to evaluate the
bioaccumulation hazard profile of CTFE despite the fact that it is
expected to rapidly partition to the atmosphere compartment, the result
of the BCFBAF model ( v.3.0, EPI Suite v 4.0) is attached. The
model prediction for CTFE yielded a BCF of 5.7 and a log Kowof
According to Annex XIII of Regulation (EC) No 1907/2006 and to the
Guidance on information requirements and chemical safety assessment
Chapter R.11 (PBT Assessment, May 2008), a substance does not fulfil the
criterion “bioaccumulative (B)” or “very bioaccumulative (vB)” if the
BCF is below 2000 and 5000, respectively, or the log Kow is below 4.5,
therefore CTFE is not expected to be bioaccumulative.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Damit Sie die Website optimal nutzen können, verwenden wir Cookies.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again