Registration Dossier
Registration Dossier
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-201-8 | CAS number: 79-38-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
Description of key information
No experimental data on CTFE biodegradation in water and sediment are available. In fact, on the grounds of the physico-chemical properties and environmental fate assessments of the substance, no release to the aquatic environment is expected. Moreover the substance profile itself indicates the difficulty to properly test CTFE and provide meaningful results of its biodegradation in aqueous systems as well as in sediment. Nevertheless, in order to evaluate the biodegradation hazard profile of CTFE, the BIOWIN v. 4.10 model has been applied. The prediction obtained from the model suggests that CTFE is not ready biodegradable. However, no adverse effects on aquatic organisms are expected because of no partitioning
of CTFE into water.
Key value for chemical safety assessment
Additional information
The biodegradation studies in surface water and in sediment (required in sections 9.2.1.2 and 9.2.1.4, respectively) of REACH (Regulation (EC) No 1907/2006) Annex IX, are not proposed by the registrant as CTFE is a gas at ambient condition with a limited water solubility and an high tendency to rapidly volatilise from water to the air.
The value of water solubility of 380 mg/l was experimentally determined in a completely sealed system with an atmosphere saturated with CTFEE. Althoughthe value of 380 mg/l itself reveals a moderate water solubility, it represents an overestimation of the actual water solubility of CTFE in the natural system since the experimental conditions did not represent the natural conditions.
The Henry’s Law constant of CTFE was calculated to be 31.500 Pa m3/mol (HENRYWIN v3.20, EPI Suite v4.0), suggesting that the substance is expected to rapidly volatilise from water to the air.
On the basis of its physico-chemical properties, CTFE is expected to primarily and rapidly partition to the atmosphere. This tendency is also confirmed by the results from the EQC Fugacity III Model (Version 2.02, The Canadian Centre for Environmental Modelling and Chemistry, May 2003) which makes absolutely remote the possibility of a CTFE partitioning into water and sediments.
Moreover the substance profile itself indicates the difficulty to properly test CTFE and provide meaningful results of its biodegradation in aqueous systems as well as in sediment.
Nevertheless an assessment based on Quantitative Structure Activity Relationships (QSARs) has been however applied as far as biodegradation is concerned.
The prediction of the BIOWIN model (BIOWIN v.4.10, EPI Suite v.4.0) suggests that CTFE is not ready biodegradable. In fact the CTFE molecule is characterized by carbon-fluorine bonds, which are the strongest bonds in organic chemistry (O'Hagan, 2008). Nevertheless no adverse effectson water and sediment organism are expected because of no partitioning of CTFE into water.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
