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Short-term toxicity to aquatic invertebrates

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Description of key information

Diuron is acutely harmful to aquatic invertebrates

Key value for chemical safety assessment

Additional information

Two short-term acute toxicity tests with Daphnia magna, according to OECD guideline 202, are available for Diuron.

A study conducted under GLP conditions and based on measured concentrations determined the EC50 (48h) to be 22.6 mg/L (Weyers, 2008). A second study, where only nominal concentrations were used, calculated the EC50 (48h) as 1.4 mg/L (Heimbach, 1983). Therefore, Diuron is found to be acutely harmful to aquatic invertebrates as evidenced by EC50 values in the range of 1.4 to 22.6 mg/L. The most conservative estimate of acute toxicity coming from the key study with and EC50 value of 1.4 mg/L (Heimbach, 1983).