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EC number: 417-220-1 | CAS number: 37441-29-5 ATIPACL
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short term toxicity to fish: LC100 (96h) > 20mg/l
Short term to aquatic invertebrates: EC100 (48h) > 20mg/l
Toxcity to aquatic algae and cyanobacteria: EC50 (72h) growth rate > 1.9 mg/l. NOEC growth rate = 1.1 mg/l.
Toxicity to microrganisms: IC50 (0.5h) > 100 mg/l
Additional information
Short-term toxicity to fish
The acute toxicity of the test item on Cyprinus carpio fish was evaluated according to EU Method C1.
The LC100 value at 96 hours was greater than 20mg/l.
Short-term toxicity to aquatic invertebrates
The aquatic toxicity of the test item to aquatic invertebrates was evaluated in a limit test according to EU Method C2.
The EC100 was found to be greater than 20 mg/l.
Toxicity to aquatic algae and cyanobacteria
The toxicity of the test item to green alga Pseudokirchneriella subcapitata was determined according to EU Method C3.
The EC50 value for inhibition of growth rate and biomass after 72 hours was > 1.9 mg/l.
Toxicity to microorganisms
The respiration inhibitory effects of the test item to the microorganisms was investigated according to EEC directive 67/548 amended November 18, 1987 (87/302), part C: Methods for the determination of ecotoxicity, publication N° L133, "Biodegradation.
Under the test conditions the substance was not toxic to waste-water bacteria.
Justification for classification
Within the CLP Regulation (EC 1272/2008), classification for acute and chronic aquatic toxicity is based on data on fish, crustacea and algae or other aquatic plants.
Acute (short-term) aquatic hazard:
In particular, classification for acute toxicity applies when LC50 (96h) on fish, and/or, EC50 (48h) on crustacea and/or ErC50 (72 or 96h) on algae is ≤ 1 mg/l.
Long-term aquatic hazard:
Substances for which adequate chronic toxicity data are not available and the substance is not readily biodegradable and/or the experimentally determined BCF≥500 (or, if absent, the log Kow≥4).
In particular, classification in:
- category chronic 1 applies for acute toxicity data ≤ 1 mg/l;
- category chronic 2 applies for acute toxicity data between 1 and 10 mg/l;
- category chronic 3 applies for acute toxicity data between 10 and 100 mg/l.
Based on the available data the test substance has toxic effects on fish, crustacea, algae and cyanobacteria trophic levels. However, the algae results to be the mosts sensitive species with an effect level (EC50) > 1.9 mg/l. For this reason the proposed classification for the test substance is Aquatic Chronic Category 2, according to the CLP Regulation (EC) 1272/2008.
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