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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment

Data source

Reference
Reference Type:
publication
Title:
Hygienic standard for 3,4-dichloronitrobenzene vapor in the air of working premises.
Author:
Belyaev VA and Kuznetsov AV
Year:
1969
Bibliographic source:
Hyg Sanit 34: 211 - 214

Materials and methods

Principles of method if other than guideline:
Method: other: no data
GLP compliance:
no
Test type:
other: migrated dataset

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
IUCLID4 Test substance: other TS: no data on purity

Test animals

Species:
rat
Strain:
other: albino
Sex:
not specified

Administration / exposure

Route of administration:
other: migrated dataset
Type of inhalation exposure:
other: migrated dataset
Vehicle:
other: migrated dataset
Duration of exposure:
4 h
Concentrations:
3, 6 or 10 mg/m³
No. of animals per sex per dose:
40
Control animals:
other: migrated dataset

Results and discussion

Any other information on results incl. tables

RS-Freetext:
<= 6 mg/m³: no adverse effects were reported

10 mg/m³: no "external" signs of intoxication; increased
number of Heinz bodies and reticulocytes and decreased
activity (13 % lower) of blood peroxidase 24 hrs after
exposure

Applicant's summary and conclusion

Executive summary:

migrated dataset