Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-140-0 | CAS number: 3010-96-6
Endpoint summary
Administrative data
Description of key information
Additional information
The acute aquatic toxicity of 2,2,4,4-tetramethyl-1,3-cyclobutanediol (TMCD) was evaluated using invertebrates (fish), vertebrates (daphnia), plants (aquatic algae), and wastewater treatment microorganisms. All of the aquatic toxicity tests were conducted according to OECD guidelines under GLP. No effects were observed in the tests with fish, daphnia and algae at mean measured concentration ≤ 106 mg/L. The inhibition of respiration in wastewater treatment microoganisms was measured over a 3 hour period. In that study the highest concentration tested, 1000 mg/L, was not inhibitory to the microorganisms (NOEC≥ 1000 mg/L). Adequate information on the aquatic toxicity hazard of TMCD has been provided with the acute studies, therefore long-term studies with fish and daphnia are not proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
