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EC number: 212-825-5
CAS number: 872-36-6
The positive control group showed a marked
increase in the incidence of micronucleated polychromatic erythrocytes
hence confirming the sensitivity of the system to the known mutagenic
activity of cyclophosphamide under the conditions of the test.
In vivo chromosome aberration potential for Vinylene carbonate was
studied in mice orally dosed once at 150, 300 or 600 mg/kg bw in
accordance with OECD 474. Reliable positive and negative controls were
There was no evidence of a significant increase in the incidence of
micronucleated polychromatic erythrocytes in animals dosed with the test
material when compared to the concurrent vehicle control groups. The
test material was concluded to be non-genotoxic under the conditions of
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