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Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: 2.g: Collection of data. Database

Data source

Reference
Reference Type:
other: Databank
Title:
Ecotox database
Author:
US EPA
Year:
2010
Bibliographic source:
http://cfpub.epa.gov/ecotox/quick_query.htm, CAS n° 140-29-4

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
yes
Details on test solutions:
PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Chemical name of vehicle (solvent):ethanol or 2-propane
- Concentration of vehicle:5 ppt
No more data

Test organisms

Test organisms (species):
Oncorhynchus mykiss (previous name: Salmo gairdneri)
Details on test organisms:
TEST ORGANISM
- Common name:rainbow trout
- Age at study initiation: fingerling
- Length at study initiation: <= 4 in

Study design

Water media type:
freshwater
Total exposure duration:
24 h

Test conditions

Test temperature:
55 F
pH:
7.5 to 8.2
Dissolved oxygen:
8.6 to 13.7 ppm
Nominal and measured concentrations:
5 mg/L

Results and discussion

Effect concentrations
Duration:
24 h
Dose descriptor:
LC0
Effect conc.:
>= 5 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The toxicity of phenylacetonitrile to Oncorhynchus mykiss was tested. Under the test conditions, the LC0(24h) is equal to or higher than 5 mg/L.
At this level of information, the test substance cannot be classified according to the CLP regulation (EC) n° 1272/2008 as the total exposure duration was less than the required 96h.
Executive summary:

The databank reports the acute toxicity of phenylacetonitrile (CAS n° 140-29-4) on Oncorhynchus mykiss (Rainbow trout). Fingerlings with a maximum size of 4 inches were exposed to 5 mg/L of test substance dissolved in 5 ppt of ethanol or 2 -propanone during 24h in fresh water with a temperature of 55 F, a pH ranging from 7.5 to 8.2 and dissolved oxygen content ranging from 8.6 to 13.7 ppm. No effects were noted, thus the LC0(24h) is equal to or higher than 5 mg/L. At this level of information, the test substance cannot be classified according to the CLP regulation (EC) n° 1272/2008 as the total exposure duration was less than the required 96h.