Registration Dossier

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
other information
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: 2.g: Collection of data. Peer-review database

Data source

Referenceopen allclose all

Reference Type:
other: Peer-reviewed database
Title:
Data bank of environmental properties of chemicals
Author:
Kemikaali
Year:
2010
Bibliographic source:
http://wwwp.ymparisto.fi/scripts/Kemrek/Kemrek.asp, CAS n° 103-50-4, Finnish Environment Insitute
Reference Type:
other: Databank
Title:
Registry of Toxic Effects of Chemical Substances
Author:
RTECS
Year:
2010
Bibliographic source:
Centre Canadien d'hygiène et de sécurité au travail, CAS n° 140-29-4

Materials and methods

Principles of method if other than guideline:
No data
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data

Sampling and analysis

Analytical monitoring:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
other: frog

Study design

Test type:
not specified
Water media type:
not specified
Remarks on exposure duration:
No data

Results and discussion

Effect concentrations
Dose descriptor:
other: LDLo
Effect conc.:
1 100 other: mg/kg
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The toxicity of phenylacetonitrile to frogs was tested by administering the substance subcutaneous. Under the test conditions, a LDLo of 1100 mg/kg was observed.
Executive summary:

The peer-reviewed databank reports that the toxicity of phenylacetonitrile (CAS n° 140-29-4) to frogs was tested when the test substance was administered subcutaneous. Under the reported conditions a LDLo was observed of 1100 mg/kg.