Registration Dossier

Administrative data

Endpoint:
bioaccumulation: aquatic / sediment
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
other information
Study period:
No data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: 2.g: Collection of data. Peer-review database
Cross-reference
Reason / purpose:
reference to same study

Data source

Reference
Reference Type:
other: Peer-reviewed database
Title:
No information
Author:
HSDB
Year:
2010
Bibliographic source:
http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB, CAS n° 140-29-4

Materials and methods

Principles of method if other than guideline:
Estimation of BCF using log Kow and a regression-derived equation
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
No data
Radiolabelling:
not specified

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
no data

Study design

Route of exposure:
other: No data
Test type:
not specified
Water / sediment media type:
not specified

Results and discussion

Bioaccumulation factor
Type:
BCF
Value:
9 dimensionless
Basis:
not specified
Remarks on result:
other: Estimation of BCF using log Kow and a regression-derived equation

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The reported BCF value of 9 is estimated based on the log Kow and a regression-derived equation. Based on this result the substance should not be considered to bioconcentrate in aquatic organisms according to the EC regulation n°1272/2008
Executive summary:

The authors estimated the bioconcentration factor of phenylacetonitrile (CAS n° 140 -29-4) using the log Kow of the substance and a regression-derived equation. The estimated BCF values of 9 indicates that phenylacetonitrile does not need to be considered to bioconcentrate in aquatic organisms according to the EC regulation n° 1272/2008.