Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-479-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicological Summary
- Administrative data
- Workers - Hazard via inhalation route
- Workers - Hazard via dermal route
- Workers - Hazard for the eyes
- Additional information - workers
- General Population - Hazard via inhalation route
- General Population - Hazard via dermal route
- General Population - Hazard via oral route
- General Population - Hazard for the eyes
- Additional information - General Population
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
The test substance registered was evaluated to be of low acute and systemic toxictiy. A read across approach is used to fill the data gap for subchronic toxicity. The read-across to PGPR is justifed as both chemicals are of comparable structures. They can be characterized as esters of polyglycerol and fatty acids and undergo the same metabolism (Refer to “Read Across Justification” presented in Section 13).
Further, the anlogue substance (source substance) PGPR is well assessed as food additive [FAC (1992) Food Advisory Committee Report on the Review of the Emulsifiers and Stabilisers in Food Regulations FdAC/REP/11. pp. 1-71. HMSO, London;GRAS Notification 009 (1998) and 179 (2006)and GRAS notice 000270: polyricinoleic acid (GRN PGPR 11-21 08)]. The Joint FAO/WHO Expert Committee on Food Additives (JECFA 17th report) set the ADI for PGPR of 7.5 mg/kg body weight (in: World Health Organization Technical Report Series 1974, No. 539 (246-253) ; FAO Nutrition Meetings Report Series, 1974, No. 53). Based on the similar structure and the same metabolism of both the target and source chemical (refer to Section 13: “Justification for Read Across”) and taken all the available data on acute and repeated dose toxicity with both the target and the source chemical together, it is considered that the target substance is of low toxicity. The NOAEL for repeated dosing is determined to be 2000 mg/kg bw/day.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
The test substance registered was evaluated to be of low acute and systemic toxictiy. A read across approach is used to fill the data gap for subchronic toxicity and reproduction toxicity. The read-across to PGPR is justifed as both chemicals are of comparable structures. They can be characterized as esters of polyglycerol and fatty acids and undergo the same metabolism (Refer to “Read Across Justification” presented in Section 13).
Further, the anlogue substance (source substance) PGPR is well assessed as food additive [FAC (1992) Food Advisory Committee Report on the Review of the Emulsifiers and Stabilisers in Food Regulations FdAC/REP/11. pp. 1-71. HMSO, London;GRAS Notification 009 (1998) and 179 (2006)and GRAS notice 000270: polyricinoleic acid (GRN PGPR 11-21 08)]. The Joint FAO/WHO Expert Committee on Food Additives (JECFA 17th report) set the ADI for PGPR of 7.5 mg/kg body weight. (in: World Health Organization Technical Report Series 1974, No. 539 (246-253) ; FAO Nutrition Meetings Report Series, 1974, No. 53). Based on the similar structure and the same metabolism of both the target and source chemical (refer to Section 13: “Justification for Read Across”) and taken all the available data on acute and repeated dose toxicity with both the target and the source chemical together, it is considered that the target substance is of low toxicity. The NOAEL for repeated dosing is determined to be 2000 mg/kg bw/day.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.