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EC number: 701-304-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- transformation / dissolution of metals and inorganic metal compounds
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2009-08-03 to 2010-03-10
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- (a) the 28-day test with a loading of 1 mg/L was conducted at pH 6 instead of 5.5 (b) the within-vessel variation was not always < 10 % (c) `mass balance (%) after completion of the transformation test´ is missing.
- Qualifier:
- according to guideline
- Guideline:
- OECD Series on Testing and Assessment No. 29 (23-Jul-2001): Guidance document on transformation/dissolution of metals and metal compounds in aqueous media
- Deviations:
- yes
- Remarks:
- please refer to the field "Rationale for reliability incl. deficiencies" above
- GLP compliance:
- yes
- Type of method:
- flask method
- Remarks:
- transformation/dissolution
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.002 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.131 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 204.019 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 8
- Type of test:
- screening transformation/dissolution test - sparingly soluble metal compounds
- Mean dissolved conc.:
- 215.745 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- pH 6
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.734 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- T = 19.7 - 21.4 °C, pH = 6 ± 0.2
- Remarks on result:
- other: SD: ± 0.0828 µg/L
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.069 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 100 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- T = 19.7 - 21.4 °C, pH = 6.00 ± 0.2
- Remarks on result:
- other: < LOD
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.224 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- T = 19.7 - 19.9 °C, pH: 6.15
- Remarks on result:
- other: < LOD
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.069 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 24 h
- Test conditions:
- T= 19.7 - 19.9 °C, pH= 6.15
- Remarks on result:
- other: < LOD
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.224 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- T = 19.7 - 21.2 °C, pH = 6.00 ± 0.2
- Remarks on result:
- other: < LOD
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.069 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 7 d
- Test conditions:
- T = 19.7 - 21.2 °C, pH = 6.00 ± 0.2
- Remarks on result:
- other: < LOD
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- 0.291 µg/L
- Element analysed:
- Fe
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- T = 19.7 - 22.4 °C, pH = 6.00 ± 0.2
- Remarks on result:
- other: SD: ± 0.0464 µg/L
- Key result
- Type of test:
- full transformation/dissolution test - metals and sparingly soluble metal compounds
- Mean dissolved conc.:
- < 0.069 µg/L
- Element analysed:
- Si
- Loading of aqueous phase:
- 1 mg/L
- Incubation duration:
- 28 d
- Test conditions:
- T = 19.7 - 22.4 °C, pH = 6.00 ± 0.2
- Remarks on result:
- other: < LOD
- Details on results:
- Silicium concentrations were below the detection limit in aqueous solutions with 1 mg/L and 100 mg/L loadings. Iron ions dissolved/transformed in aqueous solutions. At each time point dissolved Fe concentrations were < 1 μg/L.
- Conclusions:
- The transformation/dissolution of the reaction mass of fumes, silica and diiron trioxide resulted in the following dissolved concentrations:
loading, Time Fe [µg/L] Si [µg/L]
1mg/L, 7 days < 0.22 (1mg/L, 28 days 0.29+/- 0.05 < 0.07 ( 100mg/L,7 days 0.73 +/- 0.08 < 0.07 (
As dissolved Fe and Si concentrations were below 1 µg/L even at the highest loading of 100 mg/L, the pigment can be considered environmentally inert.
Reference
Test conditions were predominantly in accordance with guideline:
- Vessel Variation:
The within-vessel variations from the 100mg/L loadings for selected vessels were >10 % (not guideline comform) due to concentrations being close to the LOQ. The between-vessel variation was always ≤ 20 %.
The within-vessel variations from the 1mg/L loading for selected vessels was >10 % (not guideline comform) due to concentrations being close to the LOQ. However, the between-vessel variation was always ≤ 20 % (guideline comform).
Oxygen:
- The oxgen concentrations were in the range of 4.7 and 9.7 mg/L with three values below the acceptable limit (>70 % of air O2 concentration = 5.46 mg/L). However, a results-changing impact on dissolved Fe concentrations can be excluded.
Temperature:
- The temperature was in the range from 19.7 °C to 22.4 °C.
Solution pH:
- The pH was in the range of 6.05 to 6.19 (i.e. in the range of pH 6 + 0.2 units)
Description of key information
The solubility of High-temperature calcination products of diiron trioxide and amorphous silica resulting in a glassy silica matrix is < 0.001%. In a GLP-conform transformation/dissolution screening test with a loading of 100 mg/L a higher release was observed at pH 6 (Grane, 2010). In a short-term transformation/dissolution test with a loading of 100 mg/L at pH 6, a dissolved Fe concentration of 0.73 microg/L was determined whereas the dissolved Si concentration was below LOD (0.07 microg/L) after 7 days (Grane, 2010). Transformation/dissolution at a loading of 1 mg/L resulted in dissolved Si concentrations below the LOD (< 0.07 microg/L) at pH 6 after 7 and 28 days (Grane, 2010). The dissolved Fe concentrations at pH 6 was below the LOD (< 0.22 microg/L) after 7 and at 0.29 microg/L after 28 days (Grane, 2010). The particle size of the tested sample (BET surface area 4.21 m2/g) is representative for the particle size marketed. Thus, the extent to which "High-temperature calcination products of diiron trioxide and amorphous silica resulting in a glassy silica matrix" can produce soluble available ionic and other metal-bearing species in aqueous media is limited.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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