Registration Dossier
Registration Dossier
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EC number: 600-734-7 | CAS number: 106276-78-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The test substance is not readily biodegradable according OECD criteria.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The biodegradability of the substance was determined in a non-GLP study according to OECD 302 C (Solvias AG 2000). In this study, flasks containing about 30 mg/L test item, a reference item, abiotic control and inoculum control were incubated for 28 days. Oxygen consumption measurements were performed every one to two days. After 28-days exposure, no difference in oxygen consumption was noted. Results with the reference substance sodium benzoate showed that the test system was sufficiently sensitive. Based on these findings the substance is characterised as not readily biodegradable.
To support the results of the study three different QSARs have been calculated. All QSAR calculations (EPISuite, VEGA and CATALOGIC) gave the results that the test substance is not readily biodegradable. Even though the test substance was not within the applicability domain of some models, the results can be used as a worst-case consideration that the test substance is not readily biodegradable.
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